Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Supramolecular Interaction Between Cucurbit[8]uril and the Quinolone Antibiotic Ofloxacin

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • معلومة اضافية
    • بيانات النشر:
      CSIRO Publishing, 2019.
    • الموضوع:
      2019
    • نبذة مختصرة :
      The host–guest inclusion complex of cucurbit[8]uril (Q[8]) and ofloxacin (OFLX) has been prepared and characterised by means of 1H NMR spectroscopy, MALDI-TOF mass spectrometry, isothermal titration calorimetry (ITC), fluorescence spectroscopy, and UV-vis absorption spectroscopy. The findings demonstrated that a host–guest inclusion complex could be formed through an encapsulation of the methylmorpholine and piperazine rings in OFLX. ITC results indicated that the formation of this inclusion complex (1:1 molar ratio) was primarily dependent on enthalpy and entropy changes. In addition, the release of OFLX from the inclusion complex was increased under acidic conditions.
    • ISSN:
      0004-9425
    • الرقم المعرف:
      10.1071/ch19341
    • الرقم المعرف:
      edsair.doi...........30f80fc027f2305d4aa6cd9d429ae863