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The role of clonal evolution in smoldering multiple myeloma.

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  • معلومة اضافية
    • نبذة مختصرة :
      The article presents two case studies examining the role of clonal evolution in smoldering multiple myeloma (SMM) in a 49-year-old and a 44-year-old woman. It states despite intensive therapy, both cases had an aggressive relapse. It mentions the 49-year-old woman was treated with lenalidomide and dexamethasone with a monthly treatment of zoledronic acid but died after three years. It comments the 44-year-old woman had a similar treatment regimen and remains on bortezomib while in remission.