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Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011.
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- المؤلفون: Thoa, Le Phan Kim1; Chiang, Pai-Shan2; Khanh, Truong Huu1; Luo, Shu-Ting2; Dan, Tran Ngoc Hanh1; Wang, Ya-Fang2,3; Thuong, Tang Chi1; Chung, Wan-Yu2; Hung, Nguyen Thanh1; Wang, Jen-Ren2,3; Nhan, Le Nguyen Thanh1; Thinh, Le Quoc1; Su, Ih-Jen2,3; Dung, Than Duc1; Lee, Min-Shi2
- المصدر:
PLoS ONE. Jul2013, Vol. 8 Issue 7, p1-1. 1p.
- الموضوع:
- معلومة اضافية
- الموضوع:
- نبذة مختصرة :
Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam. [ABSTRACT FROM AUTHOR]
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