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Tumor Stem Cells in Glioblastoma Multiforme.
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- المؤلفون: Farokhpour, Mahboubeh1
- المصدر:
Emirates Journal of Food & Agriculture (EJFA). Jan2013, Vol. 25 Issue 1, p1-10. 10p.
- الموضوع:
- معلومة اضافية
- نبذة مختصرة :
Glioblastoma multiforme (GBM) is the most malignant form of brain tumors. Despite intensive treatment, the mean survival of these patients is about 1 year. Recent studies have shown that a small population of cells, called brain tumor stem cells, are resistant to chemo- and radiotherapy. They thus have the ability to reinitiate the tumor. Therefore, it seems that destroying these cells is very important for curing this disease. This review summarized the methods for isolating and enriching brain tumor stem cells. It also discussed critical signaling pathways and transcription factors that are important targets for new drugs. [ABSTRACT FROM AUTHOR]
- نبذة مختصرة :
Copyright of Emirates Journal of Food & Agriculture (EJFA) is the property of Pensoft Publishers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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