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Measurement of rabbit intraocular pressure with the Tono-Pen.

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  • المؤلفون: Mermoud A;Mermoud A; Baerveldt G; Minckler DS; Lee MB; Rao NA
  • المصدر:
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde [Ophthalmologica] 1995; Vol. 209 (5), pp. 275-7.
  • نوع النشر :
    Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Karger Country of Publication: Switzerland NLM ID: 0054655 Publication Model: Print Cited Medium: Print ISSN: 0030-3755 (Print) Linking ISSN: 00303755 NLM ISO Abbreviation: Ophthalmologica Subsets: MEDLINE
    • بيانات النشر:
      Publication: Basel : Karger
      Original Publication: Basel.
    • الموضوع:
      Intraocular Pressure*; Tonometry, Ocular/*standards; Animals ; Calibration ; Linear Models ; Rabbits ; Reference Values ; Reproducibility of Results ; Tonometry, Ocular/instrumentation
    • نبذة مختصرة :
      A Tono-Pen-1 (TP-1) and a Tono-Pen-2 (TP-2) were calibrated against direct manometry in the eyes of living rabbits to determine the accuracy of the Tono-Pen. Eighteen normal eyes of 10 rabbits were cannulated and connected to a pressure transducer with a chart recorder. Intraocular pressure (IOP) was increased from 5 to 40 mm Hg in 5-mm-Hg increments and from 40 to 80 mm Hg in 10-mm-Hg increments. After each incremental increase, IOP was measured first with a TP-1 and then with a TP-2. Plotting the mean Tono-Pen readings for each eye against the transducer pressure produced the following two regression line formulas: y = -0.613+0.790x (r2 = 0.97) for TP-1, and y = -1.45+0.824x (r2 = 0.97) for TP-2. Neither regression line was statistically different; p = 0.2 for the two slopes, and p = 0.24 for the y-axis intersection. The TP-1 and TP-2 can be used to rapidly and accurately measure the IOP in normal rabbit eyes. Tono-Pen readings do, however, significantly underestimate pressures in the range of 5-80 mm Hg. A table with 95% confidence intervals for corrected IOP readings obtained with the TP-1 or -2 is provided.
    • Grant Information:
      EXO3040 United States PHS HHS
    • الموضوع:
      Date Created: 19950101 Date Completed: 19960301 Latest Revision: 20180217
    • الموضوع:
      20240627
    • الرقم المعرف:
      10.1159/000310630
    • الرقم المعرف:
      8570152