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[Susceptibility of Clostridium difficile strains to teicoplanin and ramoplanin].

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  • معلومة اضافية
    • Transliterated Title:
      Wrazliwość szczepów Clostridium difficile na teikoplanine i ramoplaniné.
    • المصدر:
      Publisher: Panstwowy Zaklad Wydawnictw Lekarskich Country of Publication: Poland NLM ID: 0210575 Publication Model: Print Cited Medium: Print ISSN: 0025-8601 (Print) Linking ISSN: 00258601 NLM ISO Abbreviation: Med Dosw Mikrobiol Subsets: MEDLINE
    • بيانات النشر:
      Publication: Warszawa : Panstwowy Zaklad Wydawnictw Lekarskich
      Original Publication: [Warszawa, Lekarski Instytut Naukowo-Wydawniczy]
    • الموضوع:
      Depsipeptides* ; Peptides, Cyclic*; Anti-Bacterial Agents/*pharmacology ; Clostridioides difficile/*drug effects ; Teicoplanin/*pharmacology; Clostridioides difficile/isolation & purification ; Enterocolitis, Pseudomembranous/drug therapy ; Enterocolitis, Pseudomembranous/microbiology ; Humans ; Species Specificity
    • نبذة مختصرة :
      The in vitro activity of teicoplanin and ramoplanin against 113 Clostridium difficile strains isolated from different origins was determined. The minimum inhibitory concentrations (MICs) of antibiotics were determined by the agar dilution method. MIC of teicoplanin and ramoplanin were twofold lower for Clostridium difficile strains isolated from patient with pseudomembranous colitis. No correlation between the origin of the strains toxigenicity and susceptibility to teicoplanin and ramoplanin was observed. Our result indicate that teicoplanin and ramoplanin are potentially effective alternative antibiotics for treatment of infections caused by Clostridium difficile.
    • الرقم المعرف:
      0 (Anti-Bacterial Agents)
      0 (Depsipeptides)
      0 (Peptides, Cyclic)
      0WX9996O2G (ramoplanin)
      61036-62-2 (Teicoplanin)
    • الموضوع:
      Date Created: 19930101 Date Completed: 19940620 Latest Revision: 20201209
    • الموضوع:
      20250114
    • الرقم المعرف:
      8189828