Cancer stem cells: TAZ takes centre stage.

The article discusses the role of AZ gene in increasing the probability of metastasis in breast tumours. It states that TAZ is known to induce the property of self-renewal in non-cancer stem cells (CSCs), and mentions a study that determines its relationship epithelial to mesenchymal transition (EMT) activation. The study indicates that the regulation of Hippo signalling and TAZ can implicate the link of cell polarity, mesenchymal transition, and cancer development.