Effect of single or multi-period use of transcutaneous acupoint electrical stimulation on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a prospective randomized double-blind trial.

Publisher: BioMed Central Country of Publication: England NLM ID: 101761232 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-7671 (Electronic) Linking ISSN: 26627671 NLM ISO Abbreviation: BMC Complement Med Ther Subsets: MEDLINE

Original Publication: London : BioMed Central, [2020]-

Postoperative Nausea and Vomiting*/prevention & control ; Postoperative Nausea and Vomiting*/therapy ; Laparoscopy*/adverse effects ; Acupuncture Points* ; Gynecologic Surgical Procedures*/adverse effects ; Transcutaneous Electric Nerve Stimulation*/methods; Humans ; Female ; Double-Blind Method ; Adult ; Prospective Studies ; Middle Aged ; Young Adult

Competing Interests: Declarations. Consent for publication: We declare that the Publisher has the Author’s permission to publish the relevant Contribution. Informed consent: was obtained from all the subjects involved in the study. Institutional review board statement: The study was conducted in accordance with ethical standard of institution and national research committees and approved by the Ethical Committee of Linping District Maternal and Children Health Care Hospital (NO. LLSC-KYKT-2022-00016-A; 09/06/2022). Competing interests: The authors declare no competing interests.
Objective: To evaluate the efficacy of different periods for the prevention of postoperative nausea and vomiting (PONV) in patients undergoing gynecological laparoscopy with transcutaneous electrical acupoint stimulation (TEAS).
Design: Prospective, randomized, double-blind trial.
Setting: An academic medical canter specializing in the care of women and children.
Population or Sample: A total of 120 women were enrolled.
Methods: Patients were randomly allocated to three groups: a single-period TEAS group (Group S, n = 40), a multi-period TEAS group (Group M, n = 40) and a non-stimulation control group (Group C, n = 40). TEAS was applied at specific acupuncture points preoperatively and postoperatively.
Main Outcome Measures: The primary outcome was the incidence and severity of PONV during the 48 h after surgery and the secondary outcomes included pain, early recovery after surgery, and complication.
Results: Within postoperative 0-2 h, 4-12 h, group M had less frequency and lower scores for nausea compared with group C and group S had only less frequency of nausea compared with group C at 4-12 h postoperatively. The frequency and severity of vomiting for group M were less than group S in the postoperative 2-4 h. Group M mitigated pain and reduced the rescue antiemetic compared to group S.
Conclusion: Multiple-period TEAS provides greater efficacy and a longer duration of action than single-period TEAS. It effectively reduces PONV in patients undergoing gynecological laparoscopic surgery which could be a new option in multimodal prophylactic antiemetic regimes for perioperative undergoing gynecological laparoscopic surgery.
Trial Registration: Chinese Clinical Trials Registry, No. ChiCTR2200065802, Registered 15/11/2022. https//www.chictr.org.cn/bin/project/edit? pid=175,377.
(© 2025. The Author(s).)

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Keywords: Acupuncture points; Gynecological laparoscopy; Hegu (L14); Neiguan (PC6); Postoperative nausea and vomiting; Transcutaneous electric acupoint stimulation

Date Created: 20250321 Date Completed: 20250321 Latest Revision: 20250513

20250514

PMC11927246

10.1186/s12906-025-04847-5

40114162