Nut Consumption Is Associated with Cognitive Status in Southern Italian Adults.

Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

Original Publication: Basel, Switzerland : MDPI Publishing

Nuts* ; Cognition* ; Cognitive Dysfunction*/epidemiology ; Cognitive Dysfunction*/prevention & control ; Diet*; Humans ; Male ; Italy/epidemiology ; Female ; Aged ; Cross-Sectional Studies ; Middle Aged ; Diet, Mediterranean ; Aged, 80 and over ; Surveys and Questionnaires ; Logistic Models

Background: Nut consumption has been considered a potential protective factor against cognitive decline. The aim of this study was to test whether higher total and specific nut intake was associated with better cognitive status in a sample of older Italian adults.
Methods: A cross-sectional analysis on 883 older adults (>50 y) was conducted. A 110-item food frequency questionnaire was used to collect information on the consumption of various types of nuts. The Short Portable Mental Status Questionnaire was used to assess cognitive status. Multivariate logistic regression analyses were performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between nut intake and cognitive status after adjusting for potential confounding factors.
Results: The median intake of total nuts was 11.7 g/day and served as a cut-off to categorize low and high consumers (mean intake 4.3 g/day vs. 39.7 g/day, respectively). Higher total nut intake was significantly associated with a lower prevalence of impaired cognitive status among older individuals (OR = 0.35, CI 95%: 0.15, 0.84) after adjusting for potential confounding factors. Notably, this association remained significant after additional adjustment for adherence to the Mediterranean dietary pattern as an indicator of diet quality, (OR = 0.32, CI 95%: 0.13, 0.77). No significant associations were found between cognitive status and specific types of nuts.
Conclusions: Habitual nut intake is associated with better cognitive status in older adults.

Biology (Basel). 2023 Feb 09;12(2):. (PMID: 36829556)
Lancet. 2024 May 18;403(10440):2100-2132. (PMID: 38582094)
J Nutr. 2012 Jan;142(1):76-83. (PMID: 22090468)
J Med Food. 2013 Apr;16(4):343-50. (PMID: 23514229)
Lancet Public Health. 2022 Feb;7(2):e105-e125. (PMID: 34998485)
Lancet. 2020 Aug 8;396(10248):413-446. (PMID: 32738937)
Biomol Ther (Seoul). 2012 Mar;20(2):152-7. (PMID: 24116288)
Int J Food Sci Nutr. 2017 Aug;68(5):577-586. (PMID: 27919168)
Antioxidants (Basel). 2021 Apr 29;10(5):. (PMID: 33946636)
J Am Geriatr Soc. 1975 Oct;23(10):433-41. (PMID: 1159263)
Adv Nutr. 2021 Jun 1;12(3):777-792. (PMID: 33330927)
Nat Rev Neurosci. 2014 Dec;15(12):771-85. (PMID: 25387473)
Nutrients. 2020 Aug 06;12(8):. (PMID: 32781516)
J Alzheimers Dis. 2022;86(3):961-982. (PMID: 35147544)
Br J Nutr. 2014 Jun 28;111(12):2146-52. (PMID: 24642201)
Nutrients. 2021 Apr 17;13(4):. (PMID: 33920687)
Curr Alzheimer Res. 2018;15(6):531-543. (PMID: 29189157)
Br J Nutr. 2021 Mar 14;125(5):508-520. (PMID: 32713355)
Int J Food Sci Nutr. 2024 Dec 19;:1-27. (PMID: 39701663)
Clin Nutr. 2023 Nov;42(11):2258-2269. (PMID: 37826992)
Crit Rev Food Sci Nutr. 2024 Dec 4;:1-16. (PMID: 39632543)
Antioxidants (Basel). 2020 Apr 23;9(4):. (PMID: 32340112)
Open Access Maced J Med Sci. 2019 Oct 12;7(19):3253-3261. (PMID: 31949526)
Clin Nutr. 2023 Jul;42(7):1067-1075. (PMID: 37296019)
J Nutr. 2023 Jan 14;152(12):2778-2788. (PMID: 36202391)
Prostaglandins Leukot Essent Fatty Acids. 2013 Jan;88(1):97-103. (PMID: 22770766)
Nutrients. 2022 Mar 08;14(6):. (PMID: 35334794)
Pharmacol Res. 2018 Mar;129:115-127. (PMID: 29208493)
Int J Food Sci Nutr. 2024 May;75(3):336-343. (PMID: 38345046)
Geroscience. 2023 Jun;45(3):1411-1438. (PMID: 36823398)
Antioxidants (Basel). 2023 Apr 04;12(4):. (PMID: 37107256)
Int J Mol Sci. 2024 Jun 26;25(13):. (PMID: 39000076)
Geroscience. 2024 Oct;46(5):5103-5132. (PMID: 38639833)
Lipids Health Dis. 2019 Oct 15;18(1):178. (PMID: 31615571)
J Transl Med. 2024 Mar 21;22(1):294. (PMID: 38515140)
Int J Food Sci Nutr. 2023 Nov;74(7):730-745. (PMID: 37758199)
Nutrients. 2023 Feb 16;15(4):. (PMID: 36839359)
Front Pharmacol. 2019 Sep 13;10:1022. (PMID: 31607902)
Continuum (Minneap Minn). 2022 Jun 1;28(3):750-780. (PMID: 35678401)
Am J Physiol Heart Circ Physiol. 2017 Jan 1;312(1):H1-H20. (PMID: 27793855)
Int J Food Sci Nutr. 2015;66(4):426-38. (PMID: 25830946)
Redox Biol. 2024 May;71:103068. (PMID: 38377790)
Prog Lipid Res. 2022 Jan;85:101144. (PMID: 34915080)
Mol Nutr Food Res. 2024 Jan;68(1):e2300472. (PMID: 37888840)
Nutrients. 2017 May 10;9(5):. (PMID: 28489058)
Int J Food Sci Nutr. 2021 Nov;72(7):871-878. (PMID: 33541169)
Int J Food Sci Nutr. 2018 Feb;69(1):100-107. (PMID: 28562120)
Int J Environ Res Public Health. 2020 Dec 07;17(23):. (PMID: 33297407)
Geroscience. 2024 Dec;46(6):6511-6536. (PMID: 38831182)
Trends Neurosci. 2017 Apr;40(4):237-253. (PMID: 28318543)
Clin Nutr. 2021 Nov;40(11):5556-5567. (PMID: 34656952)
Am J Clin Nutr. 2023 Aug;118(2):360-368. (PMID: 37269908)
Int J Food Sci Nutr. 2023;74(4):403-423. (PMID: 37415346)
Nutrients. 2021 Sep 19;13(9):. (PMID: 34579146)
Food Nutr Res. 2023 Feb 14;67:. (PMID: 36816545)
Maturitas. 2016 Feb;84:11-6. (PMID: 26586104)
J Am Coll Nutr. 2018 Aug;37(6):494-500. (PMID: 29621433)
Int J Food Sci Nutr. 2020 Nov;71(7):783-784. (PMID: 32993403)
J Am Geriatr Soc. 1987 May;35(5):412-6. (PMID: 3571790)
Nutrients. 2020 Feb 20;12(2):. (PMID: 32093220)
Phytomedicine. 2023 Oct;119:154979. (PMID: 37552899)
Nutrients. 2022 Feb 15;14(4):. (PMID: 35215469)
Nutrients. 2024 May 16;16(10):. (PMID: 38794738)
Int J Food Sci Nutr. 2016 Nov;67(7):857-64. (PMID: 27333325)
BMJ. 2022 Mar 10;376:e068208. (PMID: 35273014)
Nutr Neurosci. 2014 Nov;17(6):241-51. (PMID: 24192577)
Prostaglandins Leukot Essent Fatty Acids. 2018 Sep;136:3-13. (PMID: 28314621)
Curr Opin Clin Nutr Metab Care. 2015 Mar;18(2):139-46. (PMID: 25501348)
Pharmacol Ther. 2022 Apr;232:108013. (PMID: 34624428)
J Int Neuropsychol Soc. 2017 Oct;23(9-10):818-831. (PMID: 29198280)

Keywords: Mediterranean diet; cognitive; nuts

Date Created: 20250213 Date Completed: 20250507 Latest Revision: 20250507

20250508

PMC11820291

10.3390/nu17030521

39940379