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L-Arginine Supplementation Did Not Impact the Rapid Recovery of Cardiovascular and Autonomic Function Following Exercise in Physically Active Healthy Males: A Triple-Blind Randomised Placebo-Controlled Crossover Trial.

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  • معلومة اضافية
    • المصدر:
      Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Basel, Switzerland : MDPI Publishing
    • الموضوع:
      Heart Rate*/drug effects ; Arginine*/administration & dosage ; Exercise*/physiology ; Dietary Supplements* ; Cross-Over Studies* ; Blood Pressure*/drug effects ; Autonomic Nervous System*/drug effects ; Autonomic Nervous System*/physiology; Humans ; Male ; Adult ; Young Adult ; Healthy Volunteers
    • نبذة مختصرة :
      Background and Aims: Post-exercise recovery strategies include massage, low-intensity active exercise, thermal contrast, hydration, and nutritional and herbal approaches. These strategies aim to accelerate recovery, enhance performance, and optimise the physical training process. L-arginine (L-ARG) is the physiological precursor of nitric oxide (NO), a crucial mediator of vasodilation and the inhibition of platelet aggregation. A previous study reported that L-ARG supplementation could significantly reduce the systolic blood pressure (SBP) and diastolic blood pressure (DBP). This study aimed to investigate the effects of L-ARG on autonomic and cardiovascular recovery immediately following submaximal exercise.
      Methods and Results: Thirty-two healthy individuals were subjected to two experimental protocols. The first protocol included 60 min of rest, a treadmill warm-up, and load increments until reaching 80% of their maximum HR. Before this protocol, the subjects consumed 3 g of starch (placebo protocol). The second protocol was identical, but the subjects consumed 3 g of L-ARG. Heart rate recovery (HRR), heart rate variability (HRV), and blood pressure (BP) responses were assessed. No significant differences in HRR were found ( p = 0.944) regarding the root mean square of successive differences in the RR interval (RMSSD30) of HRV ( p = 0.562) or in the BP responses (mean arterial pressure (MAP), p = 0.687; pulse pressure (PP), p = 0.929) between the protocols.
      Conclusions: L-ARG supplementation did not significantly alter immediate post-exercise autonomic recovery in healthy males.
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    • Grant Information:
      001 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brazil (CAPES)
    • Contributed Indexing:
      Keywords: arginine; autonomic nervous system; exercise; nitric oxide and post-exercise recovery techniques
    • الرقم المعرف:
      94ZLA3W45F (Arginine)
    • الموضوع:
      Date Created: 20241217 Date Completed: 20241217 Latest Revision: 20250117
    • الموضوع:
      20250117
    • الرقم المعرف:
      PMC11643886
    • الرقم المعرف:
      10.3390/nu16234067
    • الرقم المعرف:
      39683461