Factors influencing surgical site infections and health economic evaluation in patients undergoing robot-assisted radical resection for colorectal cancer.

Publisher: Medknow Publications Country of Publication: India NLM ID: 101249598 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1998-4138 (Electronic) Linking ISSN: 19984138 NLM ISO Abbreviation: J Cancer Res Ther Subsets: MEDLINE

Original Publication: Mumbai, India : Medknow Publications

Colorectal Neoplasms*/surgery ; Colorectal Neoplasms*/economics ; Colorectal Neoplasms*/pathology ; Surgical Wound Infection*/economics ; Surgical Wound Infection*/epidemiology ; Surgical Wound Infection*/etiology ; Robotic Surgical Procedures*/economics ; Robotic Surgical Procedures*/adverse effects ; Robotic Surgical Procedures*/methods; Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Risk Factors ; Aged ; Case-Control Studies ; Incidence ; China/epidemiology ; Length of Stay/economics ; Adult

Aims: To investigate the incidence and factors influencing surgical site infections (SSIs) in patients undergoing robot-assisted radical resection for colorectal cancer and assess their health and economic impact on the patients and hospital.
Materials and Methods: This retrospective case-controlled study comprised patients who underwent robot-assisted radical resection for colorectal cancer at a tertiary hospital in China. Information about baseline characteristics, perioperative details, postoperative SSI incidence, hospitalization costs, and follow-up was collected. Univariate and multivariate analyses were performed to identify the independent risk factors for SSI. Propensity score matching was used to evaluate the health and economic impacts of SSI on the patients and the hospital.
Results: The overall incidence of colorectal SSI in 546 patients undergoing robot-assisted radical resection for colorectal cancer was 11.72% (64/546). Intraoperative blood loss, duration of operation, preoperative absolute lymphocyte count, preoperative and postoperative serum albumin levels, tumor location, gender, history of radiotherapy or chemotherapy, surgical wound classification, and preoperative hypoalbuminemia levels were associated with SSI. Rectal cancer, male gender, and class 3 or 4 surgical wounds were identified as independent risk factors for postoperative SSI. SSI prolonged the hospital stay by 6.60 days, increased the patient's direct costs by 31,669.88 CNY, increased the economic burden by 3,262.38 CNY, and caused an indirect economic loss of 50,546.79 CNY for the hospital.
Conclusions: Patients undergoing robot-assisted radical resection for colorectal cancer are at a high risk for SSI. SSI can prolong postoperative hospital stays and increase the economic burden for patients and hospitals.
(Copyright © 2024 Journal of Cancer Research and Therapeutics.)

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Date Created: 20241206 Date Completed: 20250110 Latest Revision: 20250110

20250111

10.4103/jcrt.jcrt_1117_24

39641526