Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Association of relative handgrip strength on the development of diabetes mellitus in elderly Koreans.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • معلومة اضافية
    • المصدر:
      Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: San Francisco, CA : Public Library of Science
    • الموضوع:
    • نبذة مختصرة :
      Background: Diabetes mellitus (DM) is a significant public health concern, particularly in the elderly population. Absolute handgrip strength (HGS) serves to quantify muscle strength. It is recommended that the risk of low muscle strength and increased body mass index be concurrently evaluated using relative HGS. There are currently insufficient evidence regarding the relationship between relative HGS and DM in the elderly Korean population. Therefore, the association between relative HGS and the development of DM in Korean elderly was investigated.
      Methods: Data from the Korean Longitudinal Study of Ageing were used to determine the odds ratio (OR) between relative HGS and DM during the follow-up period from 2006-2020 among Korean men and women aged ≥65 years without DM when they first participated in this survey. Analysis was conducted using the Generalized Estimating Equation method. Trend analysis was performed for DM development based on relative HGS.
      Results: Among elderly males, higher relative HGS groups had reduced odds of developing DM (Middle tertile: OR 0.87, 95% CI 0.61-1.23, p = 0.419.) (Upper tertile: OR 0.82, 95% CI 0.56-1.18, p = 0.281.) Among elderly females, the reductions were similar. (Middle tertile: OR 0.82, 95% CI 0.66-1.03, p = 0.087.) (Upper tertile: OR 0.79, 95% CI 0.50-1.25, p = 0.306.) However, these differences were not statistically significant. Significant predictors of new-onset DM included age, BMI (overweight/obese), household income, alcohol consumption, hypertension, and chronic liver disease. Trend tests indicated a substantial decrease in the OR as the relative HGS increased for male and total groups (p for trend < 0.05).
      Conclusion: Relative HGS did not achieve statistical significance. Our findings indicate that BMI, particularly overweight and obesity, significantly predicts new-onset DM. However, trend tests indicated a substantial decrease in the OR as the relative HGS increased for male and total groups (p for trend < 0.05), even after adjusting for BMI categories. Despite the lack of statistical significance in some cases, the trend suggests that promoting resistance exercises to enhance HGS could be beneficial in DM prevention. Comprehensive DM prevention strategies should include managing obesity and chronic conditions for elderly.
      Competing Interests: The authors have declared that no competing interests exist.
      (Copyright: © 2024 Sohn et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
    • References:
      J Geriatr Oncol. 2016 May;7(3):211-8. (PMID: 27067580)
      BMC Geriatr. 2021 Jul 29;21(1):445. (PMID: 34325672)
      PLoS One. 2021 Aug 26;16(8):e0256550. (PMID: 34437604)
      Maturitas. 2017 Dec;106:92-94. (PMID: 29150172)
      Scand J Public Health. 2018 Jul;46(5):565-579. (PMID: 29528773)
      Ageing Res Rev. 2020 Dec;64:101185. (PMID: 32992047)
      Diabetes Res Clin Pract. 2007 Sep;77 Suppl 1:S87-91. (PMID: 17498834)
      Indian J Endocrinol Metab. 2015 Nov-Dec;19(6):744-52. (PMID: 26693423)
      Prev Chronic Dis. 2009 Oct;6(4):A121. (PMID: 19754997)
      J Am Geriatr Soc. 2022 Apr;70(4):1228-1235. (PMID: 34988972)
      J Arthroplasty. 2016 Jan;31(1):81-6. (PMID: 26248852)
      Diabetes Metab J. 2022 May;46(3):417-426. (PMID: 35656565)
      Diagnostics (Basel). 2022 Aug 02;12(8):. (PMID: 36010223)
      Diabetes Res Clin Pract. 2011 May;92(2):261-4. (PMID: 21281974)
      PLoS One. 2015 Sep 14;10(9):e0137739. (PMID: 26368020)
      J Lab Clin Med. 2001 Apr;137(4):231-43. (PMID: 11283518)
      Lancet. 2023 Jul 15;402(10397):203-234. (PMID: 37356446)
      Elife. 2023 Apr 19;12:. (PMID: 37073948)
      PLoS One. 2022 Oct 6;17(10):e0275746. (PMID: 36201556)
      Mech Ageing Dev. 1999 Mar 1;107(2):123-36. (PMID: 10220041)
      J Nutr Health Aging. 2010 Mar;14(3):190-5. (PMID: 20191251)
      Korean J Fam Med. 2022 May;43(3):199-205. (PMID: 35610966)
      Int J Endocrinol. 2014;2014:507395. (PMID: 25165472)
      J Health Popul Nutr. 2024 Jan 9;43(1):7. (PMID: 38195493)
      J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1525-1531. (PMID: 28329157)
      BMC Geriatr. 2022 Mar 15;22(1):206. (PMID: 35287584)
      Cell Mol Life Sci. 2012 May;69(10):1651-67. (PMID: 22101547)
      Diabetes. 2004 Feb;53(2):294-305. (PMID: 14747278)
      Front Physiol. 2018 Feb 05;9:59. (PMID: 29459831)
      PLoS One. 2016 Aug 25;11(8):e0160876. (PMID: 27559733)
    • الموضوع:
      Date Created: 20241031 Date Completed: 20241031 Latest Revision: 20241105
    • الموضوع:
      20241106
    • الرقم المعرف:
      PMC11527183
    • الرقم المعرف:
      10.1371/journal.pone.0309558
    • الرقم المعرف:
      39480796