Biosorption Ability of Pharmaceutically Active Compounds by Anabaena sp. and Chroococcidiopsis thermalis .

Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Original Publication: Basel, Switzerland : MDPI, c1995-

Anabaena*/metabolism; Diclofenac/chemistry ; Diclofenac/metabolism ; Cyanobacteria/metabolism ; Cyanobacteria/chemistry ; Biodegradation, Environmental ; Tandem Mass Spectrometry ; Adsorption ; Biomass ; Acetaminophen/chemistry ; Acetaminophen/metabolism ; Pharmaceutical Preparations/metabolism ; Pharmaceutical Preparations/chemistry

Drug overuse harms the biosphere, leading to disturbances in ecosystems' functioning. Consequently, more and more actions are being taken to minimise the harmful impact of xenopharmaceuticals on the environment. One of the innovative solutions is using biosorbents-natural materials such as cells or biopolymers-to remove environmental pollutants; however, this focuses mainly on the removal of metal ions and colourants. Therefore, this study investigated the biosorption ability of selected pharmaceuticals-paracetamol, diclofenac, and ibuprofen-by the biomass of the cyanobacteria Anabaena sp. and Chroococcidiopsis thermalis , using the LC-MS/MS technique. The viability of the cyanobacteria was assessed by determining photosynthetic pigments in cells using a UV-VIS spectrophotometer. The results indicate that both tested species can be effective biosorbents for paracetamol and diclofenac. At the same time, the tested compounds did not have a toxic effect on the tested cyanobacterial species and, in some cases, stimulated their cell growth. Furthermore, the Anabaena sp. can effectively biotransform DCF into its dimer.

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Keywords: Anabaena sp.; Chroococcidiopsis thermalis; biosorption; cyanobacteria; pharmaceuticals

144O8QL0L1 (Diclofenac)
362O9ITL9D (Acetaminophen)
0 (Pharmaceutical Preparations)

Date Created: 20240928 Date Completed: 20240928 Latest Revision: 20240930

20250114

PMC11434137

10.3390/molecules29184488

39339484