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Maternal and neonatal outcome among women with early-onset preeclampsia and late-onset preeclampsia.

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  • المؤلفون: Rahman L;Rahman L; Anwar R; Anwar R; Mose JC; Mose JC
  • المصدر:
    Hypertension in pregnancy [Hypertens Pregnancy] 2024 Dec; Vol. 43 (1), pp. 2405991. Date of Electronic Publication: 2024 Sep 21.
  • نوع النشر :
    Journal Article
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Informa Healthcare Country of Publication: England NLM ID: 9421297 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6065 (Electronic) Linking ISSN: 10641955 NLM ISO Abbreviation: Hypertens Pregnancy Subsets: MEDLINE
    • بيانات النشر:
      Publication: London : Informa Healthcare
      Original Publication: New York, NY : Marcel Dekker, Inc., c1993-
    • الموضوع:
      Pre-Eclampsia*/epidemiology ; Pregnancy Outcome*/epidemiology; Humans ; Female ; Pregnancy ; Retrospective Studies ; Adult ; Cross-Sectional Studies ; Infant, Newborn ; HELLP Syndrome/epidemiology ; Premature Birth/epidemiology ; Infant, Small for Gestational Age
    • نبذة مختصرة :
      Objective: This study aimed to determine the differences in characteristics and outcomes of early-onset and late-onset Preeclampsia.
      Methods: A retrospective cross-sectional study was conducted on female patients giving birth with preeclampsia admitted into the Department of Obstetrics and Gynecology of Dr. Hasan Sadikin Hospital Bandung from January 2020 to December 2022 who met the study criteria. A total of 435 subjects met the inclusion criteria were divided into two groups: early-onset preeclampsia and late-onset preeclampsia. Differences in outcomes were analyzed using the Chi-square or Fisher test for categorical data and the T-independent or Mann-Whitney test for numerical data.
      Results: There were differences in the incidence of HELLP syndrome (9.0 vs. 2.7%; p  = 0.009), prematurity (77.7 vs. 21.4%; p  = 0.000), early neonatal death (10.4 vs. 2.7%; p  = 0.002), asphyxia (22.7 vs. 8.0%; p  = 0.000), SGA (41.7 vs 21.9%; p  = 0.000), and LBW (78.7 vs 40.2%; p  = 0.000) in early-onset preeclampsia with late-onset. Length of stay was longer in early-onset preeclampsia cases (4.0 vs 3.0 days; p  = 0.000). Increased ureum and liver enzymes results were significantly higher in early-onset preeclampsia.
      Conclusion: There is a difference in the outcome of pregnant women with early-onset and late-onset preeclampsia. Women with early-onset preeclampsia tend to have more adverse maternal and neonatal outcomes. In terms of maternal outcome, they tend to have higher liver enzymes level and HELLP syndrome, while in terms of neonatal outcome they tend to have prematurity, early neonatal death, asphyxia, SGA, and LBW.
    • Contributed Indexing:
      Keywords: Early-onset preeclampsia; late-onset preeclampsia; maternal outcome; preeclampsia
    • الموضوع:
      Date Created: 20240921 Date Completed: 20240921 Latest Revision: 20240921
    • الموضوع:
      20250114
    • الرقم المعرف:
      10.1080/10641955.2024.2405991
    • الرقم المعرف:
      39305196