Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Precision meets generalization: Enhancing brain tumor classification via pretrained DenseNet with global average pooling and hyperparameter tuning.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • معلومة اضافية
    • المصدر:
      Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: San Francisco, CA : Public Library of Science
    • الموضوع:
    • نبذة مختصرة :
      Brain tumors pose significant global health concerns due to their high mortality rates and limited treatment options. These tumors, arising from abnormal cell growth within the brain, exhibits various sizes and shapes, making their manual detection from magnetic resonance imaging (MRI) scans a subjective and challenging task for healthcare professionals, hence necessitating automated solutions. This study investigates the potential of deep learning, specifically the DenseNet architecture, to automate brain tumor classification, aiming to enhance accuracy and generalizability for clinical applications. We utilized the Figshare brain tumor dataset, comprising 3,064 T1-weighted contrast-enhanced MRI images from 233 patients with three prevalent tumor types: meningioma, glioma, and pituitary tumor. Four pre-trained deep learning models-ResNet, EfficientNet, MobileNet, and DenseNet-were evaluated using transfer learning from ImageNet. DenseNet achieved the highest test set accuracy of 96%, outperforming ResNet (91%), EfficientNet (91%), and MobileNet (93%). Therefore, we focused on improving the performance of the DenseNet, while considering it as base model. To enhance the generalizability of the base DenseNet model, we implemented a fine-tuning approach with regularization techniques, including data augmentation, dropout, batch normalization, and global average pooling, coupled with hyperparameter optimization. This enhanced DenseNet model achieved an accuracy of 97.1%. Our findings demonstrate the effectiveness of DenseNet with transfer learning and fine-tuning for brain tumor classification, highlighting its potential to improve diagnostic accuracy and reliability in clinical settings.
      Competing Interests: The authors have declared that no competing interests exist.
      (Copyright: © 2024 Aziz et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
    • References:
      J Healthc Eng. 2022 Mar 8;2022:3264367. (PMID: 35299683)
      Cancers (Basel). 2023 Aug 18;15(16):. (PMID: 37627200)
      Comput Intell Neurosci. 2022 Jun 21;2022:1830010. (PMID: 35774437)
      Med Hypotheses. 2020 Jun;139:109696. (PMID: 32234609)
      J Digit Imaging. 2020 Aug;33(4):903-915. (PMID: 32440926)
      PLoS One. 2016 Jun 06;11(6):e0157112. (PMID: 27273091)
      Med Hypotheses. 2020 Jan;134:109531. (PMID: 31877442)
      Magn Reson Med. 2009 Dec;62(6):1609-18. (PMID: 19859947)
      J Clin Endocrinol Metab. 2004 Feb;89(2):574-80. (PMID: 14764764)
      Math Biosci Eng. 2020 Sep 15;17(5):6203-6216. (PMID: 33120595)
      PLoS One. 2015 Oct 08;10(10):e0140381. (PMID: 26447861)
      Acta Neuropathol. 2016 Jun;131(6):803-20. (PMID: 27157931)
    • الموضوع:
      Date Created: 20240906 Date Completed: 20240906 Latest Revision: 20240910
    • الموضوع:
      20250114
    • الرقم المعرف:
      PMC11379197
    • الرقم المعرف:
      10.1371/journal.pone.0307825
    • الرقم المعرف:
      39241003