The spatial-temporal distribution of hepatitis B virus infection in China,2006-2018.

Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE

Original Publication: London : BioMed Central, [2001-

Hepatitis B*/epidemiology ; Spatio-Temporal Analysis*; Humans ; China/epidemiology ; Incidence ; Hepatitis B virus ; Geographic Information Systems ; Cluster Analysis

Objectives: Hepatitis B is a liver disease caused by Hepatitis B virus (HBV) infection and is highly prevalent in China. To better understand the epidemiological characteristics of hepatitis B in China and develop effective disease control strategies, we employed temporal and spatial statistical methods.
Methods: We obtained HBV incidence data from the Public Health Science Data Center of the Chinese Center for Disease Control and Prevention for the years 2006 to 2018. Using Geographic Information System (GIS) and SaTScan scanning technology, we conducted spatial autocorrelation analysis and spatiotemporal scan analysis to create a map and visualize the distribution of hepatitis B incidence.
Results: While hepatitis B incidence rebounded in 2011 and 2017, the overall incidence in China decreased.In the trend analysis by item, the incidence varies from high to low. The global spatial autocorrelation analysis revealed a clustered distribution, and the Moran index analysis of spatial autocorrelation within local regions identified five provinces as H-H clusters (hot spots), while one province was an L-L cluster (cold spot). Spatial scan analysis identified 11 significant spatial clusters.
Conclusions: We found significant clustering in the spatial distribution of hepatitis B incidence and positive spatial correlation of hepatitis B incidence in China. We also identified high-risk times and regional clusters of hepatitis B incidence.
(© 2024. The Author(s).)

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Keywords: Cluster; Geographic information system; Hepatitis B infection; Moran’s I; Spatial epidemiology; Time-spatial distribution

Date Created: 20240811 Date Completed: 20240811 Latest Revision: 20240814

20240814

PMC11318140

10.1186/s12879-024-09716-z

39129008