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Health and Economic Benefits of Routine Childhood Immunizations in the Era of the Vaccines for Children Program - United States, 1994-2023.

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  • معلومة اضافية
    • المصدر:
      Publisher: U.S. Centers for Disease Control Country of Publication: United States NLM ID: 7802429 Publication Model: Electronic Cited Medium: Internet ISSN: 1545-861X (Electronic) Linking ISSN: 01492195 NLM ISO Abbreviation: MMWR Morb Mortal Wkly Rep Subsets: MEDLINE
    • بيانات النشر:
      Publication: Atlanta, GA : U.S. Centers for Disease Control
      Original Publication: [Atlanta] U. S. Dept. of Health, Education, and Welfare, Public Health Service, Center for Disease Control.
    • الموضوع:
      Immunization Programs*/economics; Humans ; United States ; Infant ; Child, Preschool ; Child ; Cost-Benefit Analysis ; Vaccines/administration & dosage ; Vaccines/economics ; Immunization/economics ; Immunization/statistics & numerical data
    • نبذة مختصرة :
      Since 1994, the U.S. Vaccines for Children (VFC) program has covered the cost of vaccines for children whose families might not otherwise be able to afford vaccines. This report assessed and quantified the health benefits and economic impact of routine U.S. childhood immunizations among both VFC-eligible and non-VFC-eligible children born during 1994-2023. Diphtheria and tetanus toxoids and acellular pertussis vaccine; Haemophilus influenzae type b conjugate vaccine; oral and inactivated poliovirus vaccines; measles, mumps, and rubella vaccine; hepatitis B vaccine; varicella vaccine; pneumococcal conjugate vaccine; hepatitis A vaccine; and rotavirus vaccine were included. Averted illnesses and deaths and associated costs over the lifetimes of 30 annual cohorts of children born during 1994-2023 were estimated using established economic models. Net savings were calculated from the payer and societal perspectives. Among approximately 117 million children born during 1994-2023, routine childhood vaccinations will have prevented approximately 508 million lifetime cases of illness, 32 million hospitalizations, and 1,129,000 deaths, at a net savings of $540 billion in direct costs and $2.7 trillion in societal costs. From both payer and societal perspectives, routine childhood vaccinations among children born during 1994-2023 resulted in substantial cost savings. Childhood immunizations continue to provide substantial health and economic benefits, while promoting health equity.
      Competing Interests: All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.
    • References:
      Pediatrics. 2014 Apr;133(4):577-85. (PMID: 24590750)
      MMWR Morb Mortal Wkly Rep. 2023 Nov 03;72(44):1190-1196. (PMID: 37917561)
      JAMA. 2016 Sep 13;316(10):1093-103. (PMID: 27623463)
      MMWR Morb Mortal Wkly Rep. 2023 Nov 10;72(45):1217-1224. (PMID: 37943705)
      Vaccine. 2024 Aug 13;42(20):125989. (PMID: 38806351)
      MMWR Morb Mortal Wkly Rep. 2014 Apr 25;63(16):352-5. (PMID: 24759657)
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      MMWR Morb Mortal Wkly Rep. 2020 May 15;69(19):591-593. (PMID: 32407298)
      MMWR Morb Mortal Wkly Rep. 2024 Apr 11;73(14):295-300. (PMID: 38602886)
    • الرقم المعرف:
      0 (Vaccines)
    • الموضوع:
      Date Created: 20240808 Date Completed: 20240808 Latest Revision: 20240810
    • الموضوع:
      20240812
    • الرقم المعرف:
      PMC11309373
    • الرقم المعرف:
      10.15585/mmwr.mm7331a2
    • الرقم المعرف:
      39116024