Epidemiological features of spinal intradural tumors, a single-center clinical study in Beijing, China.

Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474 (Electronic) Linking ISSN: 14712474 NLM ISO Abbreviation: BMC Musculoskelet Disord Subsets: MEDLINE

Original Publication: London : BioMed Central, [2000-

Spinal Cord Neoplasms*/epidemiology ; Spinal Cord Neoplasms*/surgery ; Ependymoma*/epidemiology ; Ependymoma*/surgery ; Ependymoma*/pathology ; Meningioma*/epidemiology ; Meningioma*/surgery ; Meningioma*/pathology ; Neurilemmoma*/epidemiology ; Neurilemmoma*/surgery ; Neurilemmoma*/pathology; Humans ; Male ; Middle Aged ; Female ; Retrospective Studies ; Adult ; Aged ; Beijing/epidemiology ; Young Adult ; Cervical Vertebrae/surgery ; Cervical Vertebrae/pathology ; Meningeal Neoplasms/epidemiology ; Meningeal Neoplasms/surgery ; Meningeal Neoplasms/pathology ; Adolescent ; Aged, 80 and over ; Thoracic Vertebrae/surgery ; Thoracic Vertebrae/pathology

Background: Spinal intradural tumors are rare and heterogeneous in histological type, aggressiveness, and symptomatology, and there is a lack of data about them. This study investigated the epidemiological features of spinal intradural tumors.
Methods: This retrospective analysis included patients with spinal intradural tumors who underwent surgical treatment at the Myelopathy and Spondylosis Ward Beijing Jishuitan Hospital between January 2012 and December 2022.
Results: This study included 1321 patients [aged 47.19 ± 14.90 years, 603 (45.65%) males] with spinal intradural tumors. The most common histological subtype was schwannoma [n = 511 (38.68%)], followed by spinal meningioma [n = 184 (13.93%)] and ependymoma [n = 101 (7.65%)]. Fifteen (1.14%) patients were diagnosed with metastatic spinal intradural tumors as a presentation of another primary cancer type. The spinal intradural tumors were mostly found in the lumbar region [n = 436 (33.01%)], followed by the thoracic vertebrae [n = 390 (29.52%)], cervical vertebrae [n = 154 (11.66%)], and thoracolumbar region [n = 111 (8.40%)]. Schwannomas mostly affected the lumbar region [n = 256 (52.64%)], spinal meningiomas in the thoracic region [n = 153 (83.15)], and ependymomas in the lumbar region [56 (55.45%)]. The de novo metastases were mostly found in the lumbar region [n = 8 (53.33%)].
Conclusion: According to the results of our single-center study, the most common spinal intradural tumor in Northern China is schwannoma, followed by spinal meningioma and ependymoma.
(© 2024. The Author(s).)

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no. PX2020018 the Beijing Municipal Administration of Hospitals Incubating Program; no. XKGG202115 the Beijing Jishuitan Hospital Elite Young Scholar Program

Keywords: Epidemiology; Retrospective study; Spinal cord diseases; Spinal cord neoplasms

Date Created: 20240801 Date Completed: 20240802 Latest Revision: 20240804

20240804

PMC11292946

10.1186/s12891-024-07741-2

39090624