Residual effect of sequential 4-channel neuromuscular electrical stimulation evaluated by high-resolution manometry.

Publisher: BioMed Central Country of Publication: England NLM ID: 101147518 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-925X (Electronic) Linking ISSN: 1475925X NLM ISO Abbreviation: Biomed Eng Online Subsets: MEDLINE

Original Publication: London : BioMed Central, [2002-

Manometry*/methods ; Deglutition*/physiology ; Electric Stimulation*; Humans ; Male ; Adult ; Female ; Pressure ; Young Adult ; Pharynx/physiology

Background: High-resolution manometry (HRM) can quantify swallowing pathophysiology to evaluate the status of the pharynx. Sequential 4-channel neuromuscular electrical stimulation (NMES) was recently developed based on the normal contractile sequences of swallowing-related muscles. This study aimed to examine the effects of sequential 4-channel NMES for compensatory application during swallowing and to observe the residual effects after the application of NMES using HRM.
Results: Sequential 4-channel NMES significantly improved the HRM parameters, with respect to the maximal pressure and area of the velopharynx (VP), maximal pressure and area of the mesopharynx (MP), and upper esophageal sphincter (UES) activation and nadir duration. Furthermore, the improvement in the pressure and area variables of the VP and MP showed a tendency to maintain even when measured after NMES, but there are no significant differences.
Conclusions: The present study suggests that the sequential 4-channel NMES application of the suprahyoid and infrahyoid muscles during swallowing improves the pressure, area, and time variables of the oropharynx, as measured by HRM, and it is likely that the effects may persist even after stimulation. Trial Registration Clinicaltrials.gov, registration number: NCT02718963 (initial release: 03/20/2016, actual study completion date: 06/24/2016, last release: 10/20/2020).
(© 2024. The Author(s).)

Am J Physiol. 1990 May;258(5 Pt 1):G675-81. (PMID: 2333995)
Ann Rehabil Med. 2017 Oct;41(5):776-785. (PMID: 29201816)
Somatosens Mot Res. 2024 Mar;41(1):34-41. (PMID: 36625230)
Neurorehabil Neural Repair. 2021 Sep;35(9):801-811. (PMID: 34218702)
Am J Phys Med Rehabil. 2019 Dec;98(12):1051-1059. (PMID: 31180928)
Dysphagia. 2011 Mar;26(1):3-12. (PMID: 21264672)
Dysphagia. 2006 Oct;21(4):243-53. (PMID: 17216386)
Ann Otol Rhinol Laryngol. 2016 Jul;125(7):541-9. (PMID: 26868604)
Ger Med Sci. 2022 Jun 14;20:Doc08. (PMID: 35875244)
Ann Rehabil Med. 2015 Apr;39(2):199-209. (PMID: 25932416)
J Electromyogr Kinesiol. 2017 Oct;36:81-89. (PMID: 28763682)
Neuromodulation. 2009 Apr;12(2):134-40. (PMID: 22151287)
Laryngoscope. 2013 Jul;123(7):1746-53. (PMID: 23417441)
Ann Otol Rhinol Laryngol. 2008 Apr;117(4):279-87. (PMID: 18478837)
J Neurogastroenterol Motil. 2016 Apr 30;22(2):231-9. (PMID: 26598598)
J Oral Rehabil. 2013 Jun;40(6):472-80. (PMID: 23607530)
Arch Phys Med Rehabil. 2017 Mar;98(3):487-494. (PMID: 27523910)
J Neuroeng Rehabil. 2021 May 31;18(1):90. (PMID: 34059092)
PLoS One. 2013 Sep 03;8(9):e69391. (PMID: 24019860)
Front Physiol. 2019 Nov 27;10:1459. (PMID: 31827446)
J Speech Lang Hear Res. 2009 Feb;52(1):240-53. (PMID: 19064903)
Head Neck. 2019 Jul;41(7):2389-2397. (PMID: 30811725)
Clin Rehabil. 2016 Jan;30(1):24-35. (PMID: 25697453)
J Speech Lang Hear Res. 2012 Jun;55(3):892-902. (PMID: 22232390)
Arch Otolaryngol Head Neck Surg. 1988 Dec;114(12):1413-8. (PMID: 3190869)
J Appl Physiol (1985). 1993 Jul;75(1):33-7. (PMID: 8376283)
Am J Phys Med Rehabil. 2020 Jun;99(6):487-494. (PMID: 31764228)
J Appl Physiol (1985). 2006 Dec;101(6):1657-63. (PMID: 16873602)
Clin Interv Aging. 2020 Sep 03;15:1521-1531. (PMID: 32943855)
Dysphagia. 2023 Jun;38(3):785-817. (PMID: 36266521)
Gerodontology. 2017 Mar;34(1):24-32. (PMID: 26694095)
J Anat. 1988 Feb;156:27-37. (PMID: 2971031)
J Rehabil Res Dev. 2009;46(2):195-204. (PMID: 19533533)
Ann Rehabil Med. 2015 Jun;39(3):425-31. (PMID: 26161349)
J Transl Med. 2022 Apr 11;20(1):175. (PMID: 35410274)
Dysphagia. 2022 Dec;37(6):1697-1714. (PMID: 35235032)
Arch Oral Biol. 2020 Mar;111:104631. (PMID: 31869725)
Ann Rehabil Med. 2015 Aug;39(4):535-44. (PMID: 26361589)
Arch Phys Med Rehabil. 2016 Mar;97(3):421-8. (PMID: 26505655)
Am J Gastroenterol. 2017 Jul;112(7):1074-1083. (PMID: 28374817)
Dysphagia. 2013 Jun;28(2):217-25. (PMID: 23242462)
Otolaryngol Head Neck Surg. 2013 Jul;149(1):126-33. (PMID: 23728150)
Phys Ther. 2018 Mar 1;98(3):172-181. (PMID: 29240948)
Muscle Nerve. 2018 Sep;58(3):441-448. (PMID: 29797723)
J Electromyogr Kinesiol. 2008 Apr;18(2):329-35. (PMID: 17187991)
J Neurogastroenterol Motil. 2015 Mar 30;21(2):283-7. (PMID: 25843079)
Clin Interv Aging. 2019 Mar 22;14:601-608. (PMID: 30962680)
Sci Rep. 2021 Mar 11;11(1):5795. (PMID: 33707528)
Int J Lang Commun Disord. 2018 Mar;53(2):405-417. (PMID: 29288590)
Adv Otorhinolaryngol. 2015;76:1-6. (PMID: 25733226)
Gerodontology. 2016 Sep;33(3):348-55. (PMID: 25393704)
Anat Rec. 2001 Dec 1;264(4):367-77. (PMID: 11745092)
J Back Musculoskelet Rehabil. 2018;31(2):363-370. (PMID: 29278871)
Medicine (Baltimore). 2022 Sep 30;101(39):e30771. (PMID: 36181078)
Brain Sci. 2023 Jan 03;13(1):. (PMID: 36672072)
Ann Otol Rhinol Laryngol. 2010 Jun;119(6):369-76. (PMID: 20583734)

NRF-2022R1A2C1007780 National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT)

Keywords: Deglutition; Dysphagia; Electrical stimulation; High-resolution manometry

ClinicalTrials.gov NCT02718963

Date Created: 20240725 Date Completed: 20240725 Latest Revision: 20240728

20240728

PMC11270850

10.1186/s12938-024-01269-1

39049019