Effect of vaccine hesitancy on female college students' willingness to receive the HPV vaccine in China: a multicenter cross-sectional study.

Publisher: BioMed Central Country of Publication: England NLM ID: 100968562 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2458 (Electronic) Linking ISSN: 14712458 NLM ISO Abbreviation: BMC Public Health Subsets: MEDLINE

Original Publication: London : BioMed Central, [2001-

Papillomavirus Vaccines*/administration & dosage ; Students*/psychology ; Students*/statistics & numerical data ; Patient Acceptance of Health Care*/statistics & numerical data ; Patient Acceptance of Health Care*/psychology ; Papillomavirus Infections*/prevention & control ; Vaccination Hesitancy*/psychology ; Vaccination Hesitancy*/statistics & numerical data; Humans ; Female ; China ; Cross-Sectional Studies ; Young Adult ; Universities ; Surveys and Questionnaires ; Adolescent ; Health Knowledge, Attitudes, Practice ; Adult

Objective: To analyse the influencing factors of vaccine hesitancy on HPV vaccination willingness of female college students in order to promote the promotion of HPV vaccine in female college student population.
Methods: From September-October 2022, a convenience sampling method was used to conduct a questionnaire survey among freshman female students from four higher vocational colleges in Henan Province, China. The survey comprised a general information questionnaire, as well as inquiries regarding vaccine hesitancy and willingness to receive the human papillomavirus (HPV) vaccine. In PSM analyses, vaccine-hesitant students were matched with non-vaccine-hesitant students at a 1:1 ratio; subsequently, both univariate and multivariatble logistic regression analyses were applied to assess the impact of vaccine hesitancy on female university students' willingness to receive the HPV vaccine.
Results: The results revealed a vaccine hesitancy rate of 44.75% among female university students, with 82.9% expressing willingness to receive the HPV vaccine. The results of the multivariable ordinal logistic regression analysis indicated vaccine hesitancy is a risk factor for HPV vaccination intentions among female university students [OR = 4.38, 95% CI (2.74, 6.99), P < 0.001]. Furthermore, the field of study (P = 0.01) and independently seeking information about the HPV vaccine (P = 0.04) were identified as factors influencing female university students' willingness to receive the HPV vaccine.
Conclusions: Non-vaccine-hesitant students were more likely to be willing to receive the HPV vaccine than vaccine-hesitant students. Healthcare providers and educators should focus on vaccine attitudes among female college students to reduce vaccine hesitancy and enhance community education on cervical cancer, HPV infection and prevention through multichannel campaigns.
(© 2024. The Author(s).)

Front Public Health. 2022 May 10;10:729497. (PMID: 35619814)
AIMS Public Health. 2021 Apr 6;8(2):352-368. (PMID: 34017897)
Hum Vaccin Immunother. 2021 Aug 3;17(8):2639-2646. (PMID: 33769209)
Hum Vaccin Immunother. 2020;16(1):116-123. (PMID: 31373874)
Lancet. 2018 Aug 4;392(10145):360. (PMID: 30102159)
Hum Vaccin Immunother. 2021 Nov 2;17(11):4163-4170. (PMID: 34370590)
Vaccines (Basel). 2020 Jan 16;8(1):. (PMID: 31963370)
Hum Vaccin Immunother. 2021 Mar 4;17(3):828-835. (PMID: 32873128)
Int J Environ Res Public Health. 2022 Oct 28;19(21):. (PMID: 36360905)
Lancet. 2011 Aug 6;378(9790):526-35. (PMID: 21664679)
Front Public Health. 2022 Feb 21;10:774767. (PMID: 35265570)
Hum Vaccin Immunother. 2018 Apr 3;14(4):924-930. (PMID: 29232166)
Front Public Health. 2022 Sep 20;10:971707. (PMID: 36203657)
Cancer Epidemiol. 2012 Aug;36(4):384-90. (PMID: 22377277)
Vaccines (Basel). 2021 Dec 03;9(12):. (PMID: 34960177)
Hum Vaccin Immunother. 2023 Dec 31;19(1):2194772. (PMID: 37005342)
Hum Vaccin Immunother. 2024 Dec 31;20(1):2309731. (PMID: 38314749)
PLoS One. 2020 Dec 11;15(12):e0243833. (PMID: 33306744)
BMC Public Health. 2024 Mar 1;24(1):667. (PMID: 38429644)
Vaccine. 2020 Aug 27;38(38):6027-6037. (PMID: 32758380)
Zhonghua Yu Fang Yi Xue Za Zhi. 2017 Sep 6;51(9):814-820. (PMID: 28881547)
J Clin Epidemiol. 2006 May;59(5):437-47. (PMID: 16632131)
BMC Infect Dis. 2017 Jul 18;17(1):502. (PMID: 28720082)
Lancet Public Health. 2020 Apr;5(4):e223-e234. (PMID: 32057317)
Vaccine. 2019 Jun 27;37(29):3918-3924. (PMID: 31160099)
J Cancer Educ. 2018 Aug;33(4):814-820. (PMID: 28074443)
PLoS Curr. 2015 Feb 25;7:. (PMID: 25789201)
CA Cancer J Clin. 2021 May;71(3):209-249. (PMID: 33538338)
Vaccines (Basel). 2020 Nov 16;8(4):. (PMID: 33207667)
Reprod Health. 2023 Dec 1;20(1):175. (PMID: 38041121)
Vaccines (Basel). 2022 Jan 31;10(2):. (PMID: 35214682)
BMC Womens Health. 2022 Feb 23;22(1):46. (PMID: 35197068)
PLoS One. 2020 Mar 19;15(3):e0230058. (PMID: 32191725)
BMC Cancer. 2016 Nov 4;16(1):848. (PMID: 27814703)
Int J Environ Res Public Health. 2019 Nov 15;16(22):. (PMID: 31731616)
Hum Vaccin Immunother. 2013 Aug;9(8):1763-73. (PMID: 23584253)
Lancet. 2015 Jun 27;385(9987):2571. (PMID: 26122153)
Med Dosw Mikrobiol. 2016;68(1):73-84. (PMID: 28146625)
Med J Aust. 2017 Apr 3;206(6):262. (PMID: 28359009)
JMIR Res Protoc. 2022 Apr 12;11(4):e36928. (PMID: 35247043)
Euro Surveill. 2010 Nov 25;15(47):. (PMID: 21144444)

Keywords: College students; HPV vaccine; Influencing factors; Vaccination intention; Vaccine hesitancy

0 (Papillomavirus Vaccines)

Date Created: 20240718 Date Completed: 20240719 Latest Revision: 20240721

20240721

PMC11256702

10.1186/s12889-024-19303-1

39026282