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Longitudinally changed diet quality scores and their association with type 2 diabetes mellitus and cardiovascular diseases in the EPIC-Potsdam study.

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  • معلومة اضافية
    • المصدر:
      Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: London : Nature Publishing Group, copyright 2011-
    • الموضوع:
      Diabetes Mellitus, Type 2*/epidemiology ; Diet, Mediterranean* ; Cardiovascular Diseases*/epidemiology ; Cardiovascular Diseases*/etiology; Humans ; Male ; Female ; Middle Aged ; Longitudinal Studies ; Myocardial Infarction/epidemiology ; Myocardial Infarction/etiology ; Stroke/epidemiology ; Stroke/etiology ; Stroke/prevention & control ; Adult ; Risk Factors ; Incidence ; Diet ; Aged ; Diet, Healthy ; Proportional Hazards Models
    • نبذة مختصرة :
      Association analyses between longitudinal changes in diet quality scores (DQIs) and cardiometabolic risk remain scarce. Hence, we aimed to investigate how changes in two DQIs are associated with incident type 2 diabetes (T2D), myocardial infarction (MI) and stroke in the EPIC-Potsdam study. Changes in the Mediterranean Pyramid Score (MedPyr) and Healthy Diet Score (HDS) over 7 years from baseline (1994-1998) to follow-up 3 (2001-2005) were investigated in 23,548 middle-aged participants. Adjusted Cox Proportional Hazards Regression models were applied to investigate associations between changes in MedPyr and HDS and chronic disease incidence. More than 60% of the participants increased both DQIs more than 5%. Within a median follow-up time of 5 years 568 cases of T2D, 171 of MI, 189 of stroke were verified. An increased compared to stable MedPyr was associated with lower T2D risk (HR 0.74; 95% CI 0.59-0.92), while a decreased MedPyr was associated with higher stroke risk (HR 1.67; 95% CI 1.02-2.72). A decreased compared to stable HDS was associated with higher stroke risk (HR 1.80; 95% CI 1.02-3.20). The findings contribute further evidence on advantages of changing dietary intake towards a Mediterranean Diet. Although baseline HDS adherence was associated with T2D and stroke risk, longitudinal changes in HDS were only significantly associated with stroke risk.
      (© 2024. The Author(s).)
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    • Grant Information:
      01EA1806A German Federal Ministry of Education and Research; 491394008 Deutsche Forschungsgemeinschaft; 01 EA 9401 Federal Ministry of Science, Germany; SOC 95201408 05F02 European Union; 70-2488-Ha I German Cancer Aid; SOC 98200769 05F02 European Community
    • Contributed Indexing:
      Keywords: Cardiovascular disease; Diet quality scores; Mediterranean diet; Type-2-diabetes mellitus
    • الموضوع:
      Date Created: 20240617 Date Completed: 20240617 Latest Revision: 20240620
    • الموضوع:
      20240620
    • الرقم المعرف:
      PMC11183239
    • الرقم المعرف:
      10.1038/s41598-024-63899-8
    • الرقم المعرف:
      38886373