Correlation between geriatric nutritional risk index and intradialytic hypotension in elderly patients undergoing maintenance hemodialysis: a case-control study.

Publisher: BioMed Central Country of Publication: Bangladesh NLM ID: 100959228 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-1315 (Electronic) Linking ISSN: 16060997 NLM ISO Abbreviation: J Health Popul Nutr Subsets: MEDLINE

Publication: May 2015- : London: BioMed Central
Original Publication: Dhaka, Bangladesh : ICDDR,B: Centre for Health and Population Research, c2000-

Renal Dialysis*/adverse effects ; Hypotension*/etiology ; Hypotension*/epidemiology ; Nutritional Status* ; Geriatric Assessment*/methods ; Geriatric Assessment*/statistics & numerical data; Humans ; Female ; Male ; Case-Control Studies ; Aged ; China/epidemiology ; Risk Factors ; Nutrition Assessment ; Risk Assessment ; Aged, 80 and over ; Middle Aged ; Kidney Failure, Chronic/therapy ; Kidney Failure, Chronic/complications

Background: There is a correlation between nutritional status and treatment outcomes and long-term survival in MHD patients but there is limited research on the relationship between GNRI and IDH. This case-control study aimed to investigate the correlation between Geriatric Nutritional Risk Index (GNRI) and intradialytic hypotension (IDH) in elderly patients undergoing maintenance hemodialysis (MHD).
Methods: This study was carried out on 129 cases of MHD patients with IDH and 258 non-IDH-controls in Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China, between June 2020 and May 2022. Professional researchers collected patients' general information on gender, primary disease, dialysis-related indicators, anthropometric measures, laboratory biochemicals, and GNRI. Logistic regression analysis was used to evaluate the correlation between GNRI and IDH.
Results: A total of 385 elderly MHD patients were included. Compared with GNRI Q4 group, the odds ratios for the risk of IDH in GNRI Q3 group, GNRI Q2 group, and GNRI Q1 group of elderly MHD patients were 1.227, 2.196, and 8.350, respectively, showing a significant downward trend (P-trend < 0.05). The area under the curve of GNRI for predicting IDH was 0.839 (95% CI: 0.799-0.879). Between different genders, a decrease in GNRI was closely related to an increase in IDH risk (P for trend < 0.05).
Conclusions: This research shows a significant association between GNRI and the incidence of IDH among elderly MHD patients and has an important warning effect. Encouraging the incorporation of GNRI assessment into the clinical assessment protocols of older patients with MHD may help to improve the nutritional status of those suffering from it and reduce the risk of IDH.
(© 2024. The Author(s).)

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2019Z17 Ruijin Hospital, Shanghai Jiaotong University School of Medicine; 2019Z17 Ruijin Hospital, Shanghai Jiaotong University School of Medicine; 2019Z17 Ruijin Hospital, Shanghai Jiaotong University School of Medicine; 2019Z17 Ruijin Hospital, Shanghai Jiaotong University School of Medicine; 2019Z17 Ruijin Hospital, Shanghai Jiaotong University School of Medicine

Date Created: 20240607 Date Completed: 20240608 Latest Revision: 20240610

20250114

PMC11161997

10.1186/s41043-024-00551-1

38849963