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Association of the CUN-BAE body adiposity estimator and other obesity indicators with cardiometabolic multimorbidity: a cross-sectional study.

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  • معلومة اضافية
    • المصدر:
      Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: London : Nature Publishing Group, copyright 2011-
    • الموضوع:
      Multimorbidity* ; Adiposity* ; Obesity*/epidemiology ; Body Mass Index* ; Waist Circumference*; Humans ; Male ; Female ; Middle Aged ; Cross-Sectional Studies ; Aged ; China/epidemiology ; Waist-Height Ratio ; Prevalence ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; ROC Curve
    • نبذة مختصرة :
      Cardiometabolic multimorbidity (CM), defined as the coexistence of two or three cardiometabolic disorders, is one of the most common and deleterious multimorbidities. This study aimed to investigate the association of Clínica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE), body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) with the prevalence of CM. The data were obtained from the 2021 health checkup database for residents of the Electronic Health Management Center in Xinzheng, Henan Province, China. 81,532 participants aged ≥ 60 years were included in this study. Logistic regression models were used to estimate the odd ratios (ORs) and 95% confidence intervals (CIs) for CUN-BAE, BMI, WC, and WHtR in CM. The area under the receiver operating characteristic curve (AUC) was used to compare the discriminatory ability of different anthropometric indicators for CM. The multivariable-adjusted ORs (95% CIs) (per 1 SD increase) of CM were 1.799 (1.710-1.893) for CUN-BAE, 1.329 (1.295-1.364) for BMI, 1.343 (1.308-1.378) for WC, and 1.314 (1.280-1.349) for WHtR, respectively. Compared with BMI, WC and WHtR, CUN-BAE had the highest AUC in both males and females (AUC: 0.642; 95% CI 0.630-0.653 for males, AUC: 0.614; 95% CI 0.630-0.653 for females). CUN-BAE may be a better measure of the adverse effect of adiposity on the prevalence of CM than BMI, WC, and WHtR.
      (© 2024. The Author(s).)
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    • Grant Information:
      2017YFC1307705 The National Key Research and Development Program "Research on prevention and control of major chronic non-communicable diseases" of China
    • الموضوع:
      Date Created: 20240508 Date Completed: 20240508 Latest Revision: 20240511
    • الموضوع:
      20240511
    • الرقم المعرف:
      PMC11078937
    • الرقم المعرف:
      10.1038/s41598-024-52164-7
    • الرقم المعرف:
      38719889