Population-Based Study of Pertussis Incidence and Risk Factors among Persons >50 Years of Age, Australia.

Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE

Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995-

Asthma*/epidemiology ; Pulmonary Disease, Chronic Obstructive* ; Whooping Cough*/epidemiology; Aged ; Female ; Humans ; Australia/epidemiology ; Incidence ; Retrospective Studies ; Risk Factors

Despite vaccination programs, pertussis has been poorly controlled, especially among older adults in Australia. This longitudinal, retrospective, observational study aimed to estimate the incidence and risk factors of pertussis among persons ≥50 years of age in Australia in the primary care setting, including those with underlying chronic obstructive pulmonary disease (COPD) or asthma. We used the IQVIA general practitioner electronic medical record database to identify patients ≥50 years of age with a clinical diagnosis of pertussis during 2015-2019. Pertussis incidence rates ranged from 57.6 to 91.4 per 100,000 persons and were higher among women and highest in those 50-64 years of age. Patients with COPD or asthma had higher incidence rates and an increased risk for pertussis compared with the overall population ≥50 years of age. Our findings suggest that persons ≥50 years of age in Australia with COPD or asthma have a higher incidence of and risk for pertussis diagnosis.

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Keywords: Australia; COPD; Pertussis; asthma; bacteria; elderly; incidence; respiratory infections; risk factors; vaccination; vaccine-preventable diseases; whooping cough

Date Created: 20231226 Date Completed: 20231227 Latest Revision: 20240102

20240102

PMC10756356

10.3201/eid3001.230261

38146987