نبذة مختصرة : Background: Poorer health and well-being are associated with diabetes risk. However, little is known about the trajectory of health and well-being from before to after diabetes diagnosis. We compared depressive symptoms, quality of life, self-rated health, and loneliness at three time points (prediagnosis, diagnosis, 2-4 years post diagnosis) in individuals who developed diabetes and a comparison group.
Methods: Health and well-being measures were self-reported by 3474 participants from the English Longitudinal Study of Ageing. Repeated measures analysis of variance and generalized estimating equations were used to investigate differences by group, time, and group-by-time interactions.
Results: A total of 473 (13.6%) participants developed diabetes. The diabetes group reported greater depressive symptoms (W 2 (1) = 20.67, p < .001) and lower quality of life (F = 1, 2535 = 10.30, p = .001) and were more likely to rate their health as fair/poor (W 2 (1) = 67.11, p < .001) across time points, adjusting for age, sex, and wealth. They also reported greater loneliness (F = 1, 2693 = 9.70, p = .002) in unadjusted analyses. However, this was attenuated to the null in adjusted analyses. The group-by-time interaction was significant for quality of life (F = 1.97, 5003.58 = 5.60, p = .004) and self-rated health (W 2 (2) = 11.69, p = .003), with a greater decline in these measures over time in the diabetes group in adjusted analyses.
Conclusion: People who received a diabetes diagnosis had greater depressive symptoms, lower quality of life, and poorer self-rated health than those who did not develop diabetes. Quality of life and self-rated health deteriorated more rapidly following a diagnosis. Screening for these factors around the time of diagnosis could allow for interventions to improve the health and well-being of those with diabetes.
(© 2023 The Authors. Journal of Diabetes published by Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.)
References: International Diabetes Federation. International Diabetes Federation Atlas, 10th edition. Available at https://www.diabetesatlas.org. 2021.
Speight J, Hendrieckx C, Pouwer F, Skinner TC, Snoek FJ. Back to the future: 25 years of ‘guidelines for encouraging psychological well-being’ among people affected by diabetes. Diabet Med. 2020;37:1225-1229.
Barnard KD, Peyrot M, Holt RIG. Psychosocial support for people with diabetes: past, present and future. Diabet Med. 2012;29:1358-1360.
Hackett RA, Steptoe A. Type 2 diabetes mellitus and psychological stress - a modifiable risk factor. Nat Rev Endocrinol. 2017;13:547-560.
Nouwen A, Winkley K, Twisk J, et al. Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis. Diabetologia. 2010;53:2480-2486.
Vancampfort D, Mitchell AJ, de Hert M, et al. Type 2 diabetes in patients with major depressive disorder: a meta-analysis of prevalence estimates and predictors. Depress Anxiety. 2015;32:763-773.
Hackett RA, Hudson JL, Chilcot J. Loneliness and type 2 diabetes incidence: findings from the English Longitudinal Study of Ageing. Diabetologia. 2020;63:2329-2338.
Feng X, Astell-Burt T. Impact of a type 2 diabetes diagnosis on mental health, quality of life, and social contacts: a longitudinal study. BMJ Open Diabetes Res Care. 2017;5:e000198.
Rotella F, Mannucci E. Diabetes mellitus as a risk factor for depression. A meta-analysis of longitudinal studies. Diabetes Res Clin Pract. 2013;99:99-104.
Christiansen J, Lund R, Qualter P, Andersen CM, Pedersen SS, Lasgaard M. Loneliness, social isolation, and chronic disease outcomes. Ann Behav Med. 2021;55:203-215.
Schunk M, Reitmeir P, Rückert-Eheberg I-M, et al. Longitudinal change in health-related quality of life in people with prevalent and incident type 2 diabetes compared to diabetes-free controls. PloS One. 2017;12:e0176895.
Hayes AJ, Clarke PM, Glasziou PG, Simes RJ, Drury PL, Keech AC. Can self-rated health scores Be used for risk prediction in patients with type 2 diabetes? Diabetes Care. 2008;31:795-797.
Noh J-W, Chang Y, Park M, Kwon YD, Ryu S. Self-rated health and the risk of incident type 2 diabetes mellitus: a cohort study. Sci Rep. 2019;9:3697.
Lin EHB, Rutter CM, Katon W, et al. Depression and advanced complications of diabetes. Diabetes Care. 2010;33:264-269.
Frank P, Batty GD, Pentti J, et al. Association between depression and physical conditions requiring hospitalization. JAMA. Psychiatry. 2023;80:690.
Messina R, Iommi M, Rucci P, et al. Is it time to consider depression as a major complication of type 2 diabetes? Evidence from a large population-based cohort study. Acta Diabetol. 2022;59:95-104.
Corno D, Burns RJ. Loneliness and functional limitations among older adults with diabetes: comparing directional models. J Psychosom Res. 2022;154:110740.
Kiadaliri AA, Najafi B, Mirmalek-Sani M. Quality of life in people with diabetes: a systematic review of studies in Iran. J Diabetes Metab Disord. 2013;12:54.
Kobos E, Szewczyk A, Kokoszka-Paszkot J, Dziedzic B. Factors associated with loneliness in patients with diabetes mellitus. Nurs Open. 2021;8:517-524.
Kusaslan Avci D. Evaluation of the relationship between loneliness and medication adherence in patients with diabetes mellitus: a cross-sectional study. J Int Med Res. 2018;46:3149-3161.
Lacruz ME, Emeny RT, Baumert J, Ladwig KH. Prospective association between self-reported life satisfaction and mortality: results from the MONICA/KORA Augsburg S3 survey cohort study. BMC Public Health. 2011;11:1-9.
Dalsgaard E-M, Vestergaard M, Skriver M, et al. Psychological distress, cardiovascular complications and mortality among people with screen-detected type 2 diabetes: follow-up of the ADDITION-Denmark trial. Diabetologia. 2014;57:710-717.
McCaffery JM, Anderson A, Coday M, et al. Loneliness relates to functional mobility in older adults with type 2 diabetes: the Look AHEAD Study. J Aging Res. 2020;2020:1-8.
Jackson SE, Williams K, Beeken RJ, Steptoe A. Changes in health and wellbeing in the years leading up to a cancer diagnosis: a prospective cohort study. Cancer Prev Res. 2019;12:79-88.
Williams K, Jackson SE, Beeken RJ, Steptoe A, Wardle J. The impact of a cancer diagnosis on health and well-being: a prospective, population-based study. Psychooncology. 2016;25:626-632.
Steptoe A, Breeze E, Banks J, Nazroo J. Cohort profile: the English longitudinal study of ageing. Int J Epidemiol. 2013;42:1640-1648.
Radloff LS. The CES-D scale. Appl Psychol Meas. 1977;1:385-401.
Steffick DE. Documentation of affective functioning measures in the Health and Retirement Study. 2000.
Hughes ME, Waite LJ, Hawkley LC, Cacioppo JT. A short scale for measuring loneliness in large surveys. Research on Aging; 2004:655-672.
Hyde M, Wiggins RD, Higgs P, Blane DB. A measure of quality of life in early old age: the theory, development and properties of a needs satisfaction model (CASP-19). Aging Ment Health. 2003;7:186-194.
Ware JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). Conceptual framework and item selection. Med Care. 1992;30:473-483.
Scott W, Jackson SE, Hackett RA. Perceived discrimination, health, and well-being among adults with and without pain: a prospective study. Pain. 2022;163:258-266.
Imkampe AK, Gulliford MC. Increasing socio-economic inequality in type 2 diabetes prevalence - repeated cross-sectional surveys in England 1994-2006. Eur J Public Health. 2011;21:484-490.
Banks J, Blundell R, Calderwood L, et al. Health, wealth and lifestyles of the older population in England. Inst Fiscal Stud. 2003;71-125.
The emerging risk factors collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol. 2007;22:839-869.
Valtorta NK, Kanaan M, Gilbody S, Hanratty B. Loneliness, social isolation and risk of cardiovascular disease in the English Longitudinal Study of Ageing. Eur. J Prev Cardiol. 2018;25:25-1396.
Dahlberg L, Agahi N, Lennartsson C. Lonelier than ever? Loneliness of older people over two decades. Arch Gerontol Geriatr. 2018;75:96-103.
Li Y, Wang X, Guo L, et al. Eight-year trajectories of late-life loneliness and incident dementia: a nationally representative cohort study. Am J Geriatr Psychiatry. 2022;31:475-486.
Rubin RR, Peyrot M. Quality of life and diabetes. Diabetes Metab Res Rev. 1999;15:205-218.
Fisher L, Glasgow RE, Mullan JT, Skaff MM, Polonsky WH. Development of a brief diabetes distress screening instrument. The. Ann Fam Med. 2008;6:6-252.
Jenkinson E, Knoop I, Hudson JL, Moss-Morris R, Hackett RA. The effectiveness of cognitive behavioural therapy and third-wave cognitive behavioural interventions on diabetes-related distress: a systematic review and meta-analysis. Diabet Med. 2022;39:e14948.
Perrin NE, Davies MJ, Robertson N, Snoek FJ, Khunti K. The prevalence of diabetes-specific emotional distress in people with type 2 diabetes: a systematic review and meta-analysis. Diabet Med. 2017;34:1508-1520.
Carper MM, Traeger L, Gonzalez JS, Wexler DJ, Psaros C, Safren SA. The differential associations of depression and diabetes distress with quality of life domains in type 2 diabetes. J Behav Med. 2014;37:501-510.
O'Donovan M, Sezgin D, O'Caoimh R, Liew A. The relationship between frailty and diabetes: an investigation of self-rated health, depression symptoms and quality of life in the study of health aging and retirement in Europe. Arch Gerontol Geriatr. 2021;96:104448.
Hackett RA, Moore C, Steptoe A, Lassale C. Health behaviour changes after type 2 diabetes diagnosis: findings from the English longitudinal study of ageing. Sci Rep. 2018;8(1):1-8.
Pastorino S, Richards M, Hardy R, et al. Validation of self-reported diagnosis of diabetes in the 1946 British birth cohort. Prim Care Diabetes. 2015;9:397-400.
_1.png)
Processing Request
No Comments.