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Is N-Hacking Ever OK? The consequences of collecting more data in pursuit of statistical significance.
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- المؤلفون: Reinagel P;Reinagel P
- المصدر:
PLoS biology [PLoS Biol] 2023 Nov 01; Vol. 21 (11), pp. e3002345. Date of Electronic Publication: 2023 Nov 01 (Print Publication: 2023).
- نوع النشر :
Journal Article
- اللغة:
English
- معلومة اضافية
- المصدر:
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
- بيانات النشر:
Original Publication: San Francisco, CA : Public Library of Science, [2003]-
- الموضوع:
- نبذة مختصرة :
Upon completion of an experiment, if a trend is observed that is "not quite significant," it can be tempting to collect more data in an effort to achieve statistical significance. Such sample augmentation or "N-hacking" is condemned because it can lead to an excess of false positives, which can reduce the reproducibility of results. However, the scenarios used to prove this rule tend to be unrealistic, assuming the addition of unlimited extra samples to achieve statistical significance, or doing so when results are not even close to significant; an unlikely situation for most experiments involving patient samples, cultured cells, or live animals. If we were to examine some more realistic scenarios, could there be any situations where N-hacking might be an acceptable practice? This Essay aims to address this question, using simulations to demonstrate how N-hacking causes false positives and to investigate whether this increase is still relevant when using parameters based on real-life experimental settings.
Competing Interests: The author has declared that no competing interests exist.
(Copyright: © 2023 Pamela Reinagel. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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- الموضوع:
Date Created: 20231101 Date Completed: 20231121 Latest Revision: 20231121
- الموضوع:
20240628
- الرقم المعرف:
PMC10619921
- الرقم المعرف:
10.1371/journal.pbio.3002345
- الرقم المعرف:
37910647
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