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UTexas Aptamer Database: the collection and long-term preservation of aptamer sequence information.
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- معلومة اضافية
- المصدر:
Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
- بيانات النشر:
Publication: 1992- : Oxford : Oxford University Press
Original Publication: London, Information Retrieval ltd.
- الموضوع:
- نبذة مختصرة :
A growing interest in aptamer research, as evidenced by the increase in aptamer publications over the years, has led to calls for a go-to site for aptamer information. A comprehensive, publicly available aptamer dataset, which may be a repository for aptamer data, standardize aptamer reporting, and generate opportunities to expand current research in the field, could meet such a demand. There have been several attempts to create aptamer databases; however, most have been abandoned or removed entirely from public view. Inspired by previous efforts, we have published the UTexas Aptamer Database, https://sites.utexas.edu/aptamerdatabase, which includes a publicly available aptamer dataset and a searchable database containing a subset of all aptamer data collected to date (1990-2022). The dataset contains aptamer sequences, binding and selection information. The information is regularly reviewed internally to ensure accuracy and consistency across all entries. To support the continued curation and review of aptamer sequence information, we have implemented sustaining mechanisms, including researcher training protocols, an aptamer submission form, data stored separately from the database platform, and a growing team of researchers committed to updating the database. Currently, the UTexas Aptamer Database is the largest in terms of the number of aptamer sequences with 1,443 internally reviewed aptamer records.
(© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.)
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- Grant Information:
52008124 United States HHMI Howard Hughes Medical Institute
- الرقم المعرف:
0 (Aptamers, Nucleotide)
- الموضوع:
Date Created: 20231031 Date Completed: 20240131 Latest Revision: 20240131
- الموضوع:
20240201
- الرقم المعرف:
PMC10767891
- الرقم المعرف:
10.1093/nar/gkad959
- الرقم المعرف:
37904593
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