Molecular surveillance and genetic diversity of Anaplasma spp. in cattle (Bos taurus) and goat (Capra aegagrus hircus) from Hainan island/province, China.

Publisher: BioMed Central Country of Publication: England NLM ID: 101249759 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-6148 (Electronic) Linking ISSN: 17466148 NLM ISO Abbreviation: BMC Vet Res Subsets: MEDLINE

Original Publication: London : BioMed Central, 2005-

Anaplasmosis*/epidemiology ; Anaplasmosis*/microbiology ; Tick-Borne Diseases*/epidemiology ; Tick-Borne Diseases*/veterinary ; Goat Diseases*/epidemiology ; Goat Diseases*/microbiology ; Cattle Diseases*/epidemiology ; Sheep Diseases*/epidemiology; Animals ; Cattle ; Sheep ; Anaplasma/genetics ; Goats/microbiology ; Ruminants/microbiology ; China/epidemiology ; Genetic Variation ; Phylogeny

Anaplasmosis is a highly prevalent tick-borne intracellular bacterial disease that affects various host species globally, particularly ruminants in tropical and subtropical regions. However, information regarding the distribution and epidemiology of anaplasmosis in small and large ruminants on Hainan Isalnd is limited. To address this knowledge gap, the present study aimed to assess the occurrence of Anaplasma spp. infections in goats (N = 731) and cattle (N = 176) blood samples using nested PCR and conventional PCR based assays. The results revealed an overall prevalence of 30.1% in goats and 14.8% in cattle. The infection rates of A. bovis, A. phagocytophilum, A. ovis and A. capra in goat samples were 22.7%, 13.8%, 2.0% and 3.4%, respectively, while the infection rates of A. bovis, A. phagocytophilum and A. marginale in cattle samples were 11.4%, 6.3% and 5.7%, respectively. A. bovis exhibited the highest prevalence among the Anaplasma spp. in both goat and cattle samples. In addition, the most frequent co-infection was the one with A. phagocytophilum and A. bovis. It was found that the age, sex and feeding habits of cattle and goats were considered to be important risk factors. Evaluation of the risk factor relating to the rearing system showed that the infection rate for the free-range goats and cattle was significantly higher when compared with stall-feeding system.This study represents one of the largest investigations on the distribution, prevalence, and risk factors associated with Anaplasma infection in ruminants on Hainan Island, highlighting a higher circulation of the infection in the region than previously anticipated. Further reasesrch is necessary to investigate tick vectors, reservoir animals, and the zoonotic potential of the Anaplasma spp. in this endemic region of Hainan Island.
(© 2023. BioMed Central Ltd., part of Springer Nature.)

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ZDKJ2021035 Major Science and Technology Plan of Hainan Province; ZDKJ2021035 Major Science and Technology Plan of Hainan Province; ZDKJ2021035 Major Science and Technology Plan of Hainan Province; ZDKJ2021035 Major Science and Technology Plan of Hainan Province; ZDKJ2021035 Major Science and Technology Plan of Hainan Province; ZDKJ2021035 Major Science and Technology Plan of Hainan Province; ZDKJ2021035 Major Science and Technology Plan of Hainan Province; ZDKJ2021035 Major Science and Technology Plan of Hainan Province; ZDKJ2021035 Major Science and Technology Plan of Hainan Province; U22A20363 National Natural Science Foundation of China; U22A20363 National Natural Science Foundation of China; U22A20363 National Natural Science Foundation of China; U22A20363 National Natural Science Foundation of China; U22A20363 National Natural Science Foundation of China; U22A20363 National Natural Science Foundation of China; U22A20363 National Natural Science Foundation of China; U22A20363 National Natural Science Foundation of China; U22A20363 National Natural Science Foundation of China

Keywords: Anaplasma; Co-infection; Hainan; Nested PCR; Ruminants

Date Created: 20231018 Date Completed: 20231023 Latest Revision: 20231122

20231215

PMC10583423

10.1186/s12917-023-03766-2

37853405