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Infection-induced seroconversion and seroprevalence of SARS-CoV-2 among a cohort of children and youth in Montreal, Canada.
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- معلومة اضافية
- المصدر:
Publisher: Wiley Country of Publication: England NLM ID: 101304007 Publication Model: eCollection Cited Medium: Internet ISSN: 1750-2659 (Electronic) Linking ISSN: 17502640 NLM ISO Abbreviation: Influenza Other Respir Viruses Subsets: MEDLINE
- بيانات النشر:
Original Publication: Oxford, UK : Wiley, c2007-
- الموضوع:
- نبذة مختصرة :
The EnCORE study is a prospective serology study of SARS-CoV-2 in a cohort of children from Montreal, Canada. Based on data from our fourth round of data collection (May-October 2022), we estimated SARS-CoV-2 seroprevalence and seroconversion. Using multivariable regression, we identified factors associated with seroconversion. Our results show that previously seronegative children were approximately 9-12 times more likely to seroconvert during the early Omicron-dominant period compared to pre-Omicron rounds. Unlike the pre-Omicron rounds, the adjusted rate of seroconversion among 2- to 4-year-olds was higher than older age groups. As seen previously, higher seroconversion rates were associated with ethnic/racial minority status.
Competing Interests: JP reports grants from MedImmune, grants and personal fees from Merck and AbbVie, and personal fees from AstraZeneca, all outside the submitted work.
(© 2023 The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd.)
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- Contributed Indexing:
Keywords: Canada; SARS‐CoV‐2; adolescents; children; seroconversion; seroprevalence
- الموضوع:
Date Created: 20230828 Date Completed: 20230829 Latest Revision: 20231106
- الموضوع:
20231215
- الرقم المعرف:
PMC10457549
- الرقم المعرف:
10.1111/irv.13186
- الرقم المعرف:
37638094
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