Serosurveillance of SARS-CoV-2 in companion animals in Sarawak, Malaysia.

Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-422X (Electronic) Linking ISSN: 1743422X NLM ISO Abbreviation: Virol J Subsets: MEDLINE

Original Publication: [London] : BioMed Central, 2004-

COVID-19*/epidemiology ; COVID-19*/veterinary ; Cat Diseases*/epidemiology ; Dog Diseases*/epidemiology; Animals ; Cats ; Dogs ; SARS-CoV-2 ; Pets ; Malaysia/epidemiology ; Seroepidemiologic Studies

SARS-CoV-2 is a zoonotic betacoronavirus that was first reported at the dawn of 2019 in Wuhan, China and has since spread globally, causing an ongoing pandemic. Anthroponotic transmission was reported early, with confirmed infections reported in 26 species to date, including dogs and cats. However, there is a paucity of reports on the transmission of SARS-CoV-2 to companion animals, and thus, we aimed to estimate the seroprevalence of SARS-CoV-2 in dogs and cats in Sarawak, Malaysia. From August 2022 to 2023, we screened plasma samples of 172 companion animals in Sarawak, Malaysia, using a species-independent surrogate virus neutralization test. Our findings revealed the presence of neutralizing antibodies of SARS-CoV-2 in 24.5% (27/110) of dogs and 24.2% (15/62) of cats. To the best of our knowledge, this is the first report of the seroprevalence of SARS-CoV-2 in companion animals in Malaysia. Our findings emphasize the need for pet owners to distance themselves from their pets when unwell, and a strategy must be in place to monitor SARS-CoV-2 in companion animals to assess the potential impact of the virus on companion animals.
(© 2023. BioMed Central Ltd., part of Springer Nature.)

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Keywords: Cats; Dogs; Neutralizing antibodies; SARS-CoV-2; Seroprevalence; cPASS

Date Created: 20230807 Date Completed: 20230809 Latest Revision: 20231121

20250114

PMC10408157

10.1186/s12985-023-02133-9

37550752