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Optimizing Small-Molecule Synthesis.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • المؤلفون: van Arnum, Patricia
  • المصدر:
    Pharmaceutical Technology. Jan2009, Vol. 33 Issue 1, p58-61. 3p.
  • معلومة اضافية
    • الموضوع:
      INTERMEDIATES (Chemistry); ORGANIC compounds; CATALYSIS; BIOSYNTHESIS; BIOCHEMISTRY; TRAUNER, Dirk
    • نبذة مختصرة :
      The article discusses the optimization of the synthesis of intermediates or small-molecule active pharmaceutical ingredients (APIs). It examines various approaches for next-generation catalysis for olefin metathesis, polymeric catalysis for aldol reactions, and biomimetic synthesis of natural product-based APIs. According to Dirk Trauner, professor for chemical biology and genetics, large majority of natural products are still unknown.