Long-term poor sleep quality is associated with adverse donor reactions in college students in Central China: A population-based cross-sectional study.

Publisher: Blackwell Science Country of Publication: England NLM ID: 0413606 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1423-0410 (Electronic) Linking ISSN: 00429007 NLM ISO Abbreviation: Vox Sang Subsets: MEDLINE

Publication: 2001- : Oxford, UK : Blackwell Science
Original Publication: Basel : Karger

Sleep Quality* ; Drug-Related Side Effects and Adverse Reactions*; Humans ; Cross-Sectional Studies ; Students ; China/epidemiology ; Blood Donors

Background and Objectives: Adverse donor reaction (ADR) could adversely impact the recruitment and retention of blood donors, but the evidence of effect of sleep quality on ADR is limited and controversial. The goal of this study was to explore the association between the sleep quality and ADR among college students in Wuhan.
Materials and Methods: The college student blood donors in Wuhan from March to May 2022 were recruited. Self-compiled general information questionnaire and Pittsburgh sleep quality index (PSQI) were investigated by convenience sampling. Univariable and multivariable logistic regression analyses were used to estimate the association.
Results: Among 1014 participants included in this study, 63 were in the ADR group and 951 were in the non-ADR group. Compared with the non-ADR group, the PSQI scores of ADR group were higher (3.44 ± 1.81 vs. 2.78 ± 1.82, p < 0.01). The results of multivariable logistic regression analysis showed that after adjusting gender, body mass index, blood donation history and other potential confounding factors, higher PSQI scores were related to the occurrence of ADRs (odds ratio = 1.231, 95% confidence interval 1.075-1.405), that is, the worse the sleep quality, the more likely the ADRs will occur.
Conclusion: The long-term poor sleep quality of college students is a risk factor for the occurrence of ADRs. It should be identified early before blood donation to reduce the incidence of ADRs and improve the safety and satisfaction of donors.
(© 2023 International Society of Blood Transfusion.)

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2021 Hubei Provincial Public Health Youth Top Talent Program; WG21D04 Medical Research Project of Wuhan Municipal Health Commission

Keywords: adverse donor reaction; college students; sleep quality

Date Created: 20230516 Date Completed: 20230616 Latest Revision: 20230616

20231215

10.1111/vox.13438

37191246