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Neuropsychiatric post-acute sequelae of COVID-19: prevalence, severity, and impact of vaccination.
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- المؤلفون: Elmazny A;Elmazny A;Elmazny A; Magdy R; Magdy R; Hussein M; Hussein M; Elsebaie EH; Elsebaie EH; Ali SH; Ali SH; Abdel Fattah AM; Abdel Fattah AM; Hassan M; Hassan M; Yassin A; Yassin A; Mahfouz NA; Mahfouz NA; Elsayed RM; Elsayed RM; Fathy W; Fathy W; Abdel-Hamid HM; Abdel-Hamid HM; Abdelbadie M; Abdelbadie M; Soliman SH; Soliman SH
- المصدر:
European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2023 Sep; Vol. 273 (6), pp. 1349-1358. Date of Electronic Publication: 2023 Jan 27.- نوع النشر :
Journal Article- اللغة:
English - المصدر:
- معلومة اضافية
- المصدر: Publisher: Springer International Country of Publication: Germany NLM ID: 9103030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-8491 (Electronic) Linking ISSN: 09401334 NLM ISO Abbreviation: Eur Arch Psychiatry Clin Neurosci Subsets: MEDLINE
- بيانات النشر: Original Publication: Berlin ; New York : Springer International, c1990-
- الموضوع:
- نبذة مختصرة : The potential long-term neuropsychiatric effects of COVID-19 are of global concern. This study aimed to determine the prevalence and predictors of neuropsychiatric post-acute sequelae of COVID-19 among Egyptian COVID-19 survivors and to study the impact of full vaccination before COVID-19 infection on the occurrence and severity of these manifestations. Three months after getting COVID-19 infection, 1638 COVID-19 survivors were screened by phone for possible neuropsychiatric sequelae. Subjects suspected to suffer from these sequelae were invited to a face-to-face interview for objective evaluation. They were requested to rate the severity of their symptoms using visual analogue scales (VAS). The mean age of participants was 38.28 ± 13 years. Only 18.6% were fully vaccinated before COVID-19 infection. Neuropsychiatric post-acute sequelae of COVID-19 were documented in 598 (36.5%) subjects, fatigue was the most frequent one (24.6%), followed by insomnia (16.4%), depression (15.3%), and anxiety (14.4%). Moderate and severe COVID-19 infection and non-vaccination increased the odds of developing post-COVID-19 neuropsychiatric manifestations by 2 times (OR 1.95, 95% CI = 1.415-2.683), 3.86 times (OR 3.86, 95% CI = 2.358-6.329), and 1.67 times (OR 1.67, 95% CI = 1.253-2.216), respectively. Fully vaccinated subjects before COVID-19 infection (n = 304) had significantly lesser severity of post-COVID-19 fatigue, ageusia/hypogeusia, dizziness, tinnitus, and insomnia (P value = 0.001, 0.008, < 0.001, 0.025, and 0.005, respectively) than non-vaccinated subjects. This report declared neuropsychiatric sequelae in 36.5% of Egyptian COVID-19 survivors, fatigue being the most prevalent. The effectiveness of COVID-19 vaccines in reducing the severity of some post-COVID-19 neuropsychiatric manifestations may improve general vaccine acceptance.
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- الرقم المعرف: 0 (COVID-19 Vaccines)
- الموضوع: Date Created: 20230127 Date Completed: 20230825 Latest Revision: 20230825
- الموضوع: 20231215
- الرقم المعرف: PMC9882743
- الرقم المعرف: 10.1007/s00406-023-01557-2
- الرقم المعرف: 36707454
- المصدر:
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