Association of Calcium, Magnesium, Zinc, and Copper Intakes with Diabetic Retinopathy in Diabetics: National Health and Nutrition Examination Survey, 2007-2018.

Publisher: Informa Healthcare Country of Publication: England NLM ID: 8104312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2202 (Electronic) Linking ISSN: 02713683 NLM ISO Abbreviation: Curr Eye Res Subsets: MEDLINE

Publication: London : Informa Healthcare
Original Publication: London : IRL Press, [c1981-

Diabetic Retinopathy*/epidemiology ; Diabetes Mellitus*/epidemiology; Adult ; Humans ; Zinc ; Magnesium ; Copper ; Nutrition Surveys ; Calcium

Purpose: To evaluate the associations between calcium, magnesium, zinc, and copper intakes and the risk of diabetic retinopathy (DR) in US diabetes adults.
Methods: Using data from the National Health and Nutrition Examination Survey (NHANES) 2007-2018. Multivariable logistic regression models and restricted cubic spline models were applied to examine the associations between total calcium, magnesium, zinc, and copper intakes and diabetic retinopathy.
Results: A total of 3794 adults aged 40 years or older were included. Higher quartile intake of calcium, magnesium, zinc, and copper was associated with a lower occurrence of DR, the multivariate adjusted ORs (95% CI) were 0.57 (0.38-0.86), 0.48 (0.32-0.73), 0.58 (0.39-0.88), and 0.48 (0.30-0.77), respectively. U-shaped dose-response relationships were found between calcium, magnesium, zinc, copper intake, and the risk of DR.
Conclusion: Higher total calcium, magnesium, zinc, and copper intake were inversely associated with the risk of DR in US diabetes adults.

Keywords: Diabetic retinopathy; calcium; copper; magnesium; zinc

J41CSQ7QDS (Zinc)
I38ZP9992A (Magnesium)
789U1901C5 (Copper)
SY7Q814VUP (Calcium)

Date Created: 20230105 Date Completed: 20230419 Latest Revision: 20230420

20240829

10.1080/02713683.2023.2165105

36601653