The demographic history of house mice (Mus musculus domesticus) in eastern North America.

Publisher: Oxford University Press Country of Publication: England NLM ID: 101566598 Publication Model: Print Cited Medium: Internet ISSN: 2160-1836 (Electronic) Linking ISSN: 21601836 NLM ISO Abbreviation: G3 (Bethesda) Subsets: MEDLINE

Publication: 2021- : [Oxford] : Oxford University Press
Original Publication: Bethesda, MD : Genetics Society of America, 2011-

Mice*/genetics ; Genetic Variation*; Animals ; Europe ; North America ; Phylogeny ; Genetics, Population

The Western European house mouse (Mus musculus domesticus) is a widespread human commensal that has recently been introduced to North America. Its introduction to the Americas is thought to have resulted from the transatlantic movements of Europeans that began in the early 16th century. To study the details of this colonization history, we examine population structure, explore relevant demographic models, and infer the timing of divergence among house mouse populations in the eastern United States using published exome sequences from five North American populations and two European populations. For North American populations of house mice, levels of nucleotide variation were lower, and low-frequency alleles were less common than for European populations. These patterns provide evidence of a mild bottleneck associated with the movement of house mice into North America. Several analyses revealed that one North American population is genetically admixed, which indicates at least two source populations from Europe were independently introduced to eastern North America. Estimated divergence times between North American and German populations ranged between ∼1,000 and 7,000 years ago and overlapped with the estimated divergence time between populations from Germany and France. Demographic models comparing different North American populations revealed that these populations diverged from each other mostly within the last 500 years, consistent with the timing of the arrival of Western European settlers to North America. Together, these results support a recent introduction of Western European house mice to eastern North America, highlighting the effects of human migration and colonization on the spread of an invasive human commensal.
Competing Interests: Conflicts of interest None declared.
(© The Author(s) 2022. Published by Oxford University Press on behalf of the Genetics Society of America.)

Mol Ecol. 2008 Dec;17(24):5349-63. (PMID: 19121002)
Bioinformatics. 2012 Sep 15;28(18):2366-73. (PMID: 22811546)
Nature. 2009 Sep 24;461(7263):489-94. (PMID: 19779445)
Integr Zool. 2012 Sep;7(3):247-253. (PMID: 22938522)
Proc Biol Sci. 2016 Oct 26;283(1841):. (PMID: 27798305)
Genome Biol Evol. 2019 Mar 1;11(3):844-854. (PMID: 30715331)
Nat Commun. 2016 Aug 23;7:12485. (PMID: 27549569)
Genetics. 2012 Nov;192(3):1065-93. (PMID: 22960212)
PLoS Genet. 2018 Sep 24;14(9):e1007672. (PMID: 30248095)
Curr Biol. 2012 Feb 21;22(4):302-8. (PMID: 22264611)
Heredity (Edinb). 2022 Sep;129(3):183-194. (PMID: 35764696)
J Evol Biol. 2015 Jan;28(1):130-45. (PMID: 25394749)
Genome Biol. 2016 Jun 06;17(1):122. (PMID: 27268795)
Genetics. 2013 Apr;193(4):1233-54. (PMID: 23410830)
Mamm Genome. 2013 Feb;24(1-2):1-20. (PMID: 23223940)
Bioinformatics. 2014 May 1;30(9):1312-3. (PMID: 24451623)
Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):196-201. (PMID: 25512534)
Mol Ecol. 2014 Apr;23(8):1923-39. (PMID: 24617968)
Genetics. 2000 Apr;154(4):1785-91. (PMID: 10747069)
PLoS Genet. 2009 Oct;5(10):e1000695. (PMID: 19851460)
BMC Biol. 2010 Oct 26;8:131. (PMID: 20977781)
Bioinformatics. 2011 Nov 1;27(21):2987-93. (PMID: 21903627)
Sci Data. 2016 Sep 13;3:160075. (PMID: 27622383)
Bioinformatics. 2011 Aug 1;27(15):2156-8. (PMID: 21653522)
PLoS Genet. 2012;8(11):e1002967. (PMID: 23166502)
PLoS One. 2011;6(11):e26357. (PMID: 22073158)
Gigascience. 2020 Mar 1;9(3):. (PMID: 32112099)
Curr Biol. 2011 Aug 9;21(15):1296-301. (PMID: 21782438)
Genome Biol Evol. 2022 Jan 4;14(1):. (PMID: 35038727)
J Hered. 2006 Mar-Apr;97(2):107-13. (PMID: 16489143)
Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11261-11265. (PMID: 27638204)
Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4099-4104. (PMID: 28348225)
Genet Sel Evol. 2018 Nov 19;50(1):59. (PMID: 30449279)
Trends Genet. 2013 May;29(5):298-308. (PMID: 23290437)
Mol Ecol. 2005 May;14(6):1655-66. (PMID: 15836640)
Elife. 2015 Apr 15;4:. (PMID: 25875302)
BMC Evol Biol. 2012 Mar 19;12:35. (PMID: 22429664)
BMC Bioinformatics. 2014 Nov 25;15:356. (PMID: 25420514)
Am J Hum Genet. 2007 Sep;81(3):559-75. (PMID: 17701901)
Sci Rep. 2020 May 19;10(1):8276. (PMID: 32427845)
Genome Res. 2009 Sep;19(9):1655-64. (PMID: 19648217)
Bioinformatics. 2010 Mar 15;26(6):841-2. (PMID: 20110278)
Genetics. 1989 Nov;123(3):585-95. (PMID: 2513255)
Heredity (Edinb). 2013 Nov;111(5):375-90. (PMID: 23820581)
Proc Biol Sci. 2009 Jan 22;276(1655):201-7. (PMID: 18826939)

R01 GM127468 United States GM NIGMS NIH HHS

Keywords: Mus musculus domesticus; demographic inference; population genetics

Date Created: 20221222 Date Completed: 20230213 Latest Revision: 20240222

20240222

PMC9911051

10.1093/g3journal/jkac332

36546306