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Lymphadenopathies before and during the Pandemic COVID-19: Increasing Incidence of Metastases from Solid Tumors.

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  • معلومة اضافية
    • المصدر:
      Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE
    • بيانات النشر:
      Original Publication: Basel, Switzerland : MDPI AG, [2012]-
    • نبذة مختصرة :
      Since December 2019, the world has experienced a pandemic caused by SARS-CoV-2, a virus which spread throughout the world. Anti-COVID19 measures were applied to limit the spread of the infection, affecting normal clinical practice. In 2020, studies on the possible impact of the pandemic considering the screening programs for early diagnosis of cancer were conducted, resulting in a prediction of delayed diagnosis of cancer. We performed a retrospective monocentric study on patients who present with the onset of lymphadenomegalies evaluated at our Hematological Department from February 2019 to October 2021 and undergoing excisional lymph-node biopsy. Three periods were considered: pre-pandemic, first pandemic period and second pandemic period (Group A, B and C). We included 258 patients who underwent a surgical biopsy and received a histological diagnosis. Hematological evaluation of outpatients sent by the general practitioner and surgical biopsies did not decrease among the three groups, despite limitations placed during this pandemic as well as new diagnoses of hematological malignancies. However, the diagnosis of metastatic cancer significantly increased from 2019 (7.8%) to 2021 (22.1%) ( p = 0.042). Our data supports the hypothesis that the pandemic affected the national screening programs of early cancer detection.
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    • Contributed Indexing:
      Keywords: hematological malignancies; lymph-node biopsy; lymphadenopathies; metastatic cancers; pandemic COVID-19; screening; solid tumors
    • الموضوع:
      Date Created: 20221211 Latest Revision: 20221221
    • الموضوع:
      20240829
    • الرقم المعرف:
      PMC9739990
    • الرقم المعرف:
      10.3390/jcm11236979
    • الرقم المعرف:
      36498559