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Costs and Factors Associated with Hospitalizations Due to Severe Influenza in Catalonia (2017-2020).

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  • معلومة اضافية
    • المصدر:
      Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238455 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-4601 (Electronic) Linking ISSN: 16604601 NLM ISO Abbreviation: Int J Environ Res Public Health Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Basel : MDPI, c2004-
    • الموضوع:
      Influenza Vaccines*/therapeutic use ; Influenza, Human*/prevention & control; Pregnancy ; Female ; Humans ; Spain/epidemiology ; Cross-Sectional Studies ; Hospitalization
    • نبذة مختصرة :
      This study aimed to estimate the cost and factors associated with severe hospitalized patients due to influenza in unvaccinated and vaccinated cases. The study had a cross-sectional design and included three influenza seasons in 16 sentinel hospitals in Catalonia, Spain. Data were collected from a surveillance system of influenza and other acute respiratory infections. Generalized linear models (GLM) were used to analyze mean costs stratified by comorbidities and pregnancy. Multivariate logistic models were used to analyze bacterial coinfection, multi-organ failure, acute respiratory distress syndrome, death and ICU admission by season and by vaccination status. Costs of ICU, hospitalization and total mean costs were analyzed using GLM, by season and by vaccination status. All models were adjusted for age and sex. A total of 2742 hospitalized cases were included in the analyses. Cases were mostly aged ≥ 60 years (70.17%), with recommended vaccination (86.14%) and unvaccinated (68.05%). The ICU admission level was statistically significant higher in unvaccinated compared to vaccinated cases. Costs of cases with more than or equal to two comorbidities (Diff = EUR - 1881.32), diabetes (Diff = EUR - 1953.21), chronic kidney disease (Diff = EUR - 2260.88), chronic cardiovascular disease (Diff = EUR - 1964.86), chronic liver disease (Diff = EUR - 3595.60), hospitalization (EUR 9419.42 vs. EUR 9055.45), and total mean costs (EUR 11,540.04 vs. 10,221.34) were statistically significant higher in unvaccinated compared to vaccinated patients. The influenza vaccine reduces the costs of hospitalization. There is a need to focus strategies in recommended vaccination groups.
    • References:
      BMC Infect Dis. 2016 Jan 08;16:6. (PMID: 26743673)
      J Healthc Qual Res. 2022 Jul-Aug;37(4):201-207. (PMID: 35165077)
      Lancet. 2018 Mar 31;391(10127):1285-1300. (PMID: 29248255)
      PLoS One. 2019 Jan 11;14(1):e0210353. (PMID: 30633778)
      Influenza Other Respir Viruses. 2018 Jan;12(1):22-29. (PMID: 29197154)
      PLoS One. 2018 Sep 7;13(9):e0202787. (PMID: 30192781)
      Gac Sanit. 2021 Jul-Aug;35(4):339-344. (PMID: 32331814)
      Eur J Health Econ. 2020 Jul;21(5):775-785. (PMID: 32180069)
      N Engl J Med. 2007 Oct 4;357(14):1373-81. (PMID: 17914038)
      PLoS One. 2017 Jan 26;12(1):e0170550. (PMID: 28125629)
      Med Intensiva. 2009 Dec;33(9):455-8. (PMID: 19854543)
      PLoS One. 2015 Mar 04;10(3):e0118369. (PMID: 25738736)
      Int J Environ Res Public Health. 2019 Mar 01;16(5):. (PMID: 30832264)
      Eur J Health Econ. 2022 Feb;23(1):67-80. (PMID: 34283323)
    • Contributed Indexing:
      Keywords: comorbidity; hospital costs; hospitalization; influenza vaccination
    • الرقم المعرف:
      0 (Influenza Vaccines)
    • الموضوع:
      Date Created: 20221126 Date Completed: 20221129 Latest Revision: 20230130
    • الموضوع:
      20240829
    • الرقم المعرف:
      PMC9690392
    • الرقم المعرف:
      10.3390/ijerph192214793
    • الرقم المعرف:
      36429510