Prevalence of Antimicrobial Prescribing in Long-Term Care Facilities in a Local Health Authority of Northern Italy.

Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238455 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-4601 (Electronic) Linking ISSN: 16604601 NLM ISO Abbreviation: Int J Environ Res Public Health Subsets: MEDLINE

Original Publication: Basel : MDPI, c2004-

Drug Utilization* ; Anti-Infective Agents*/therapeutic use; Humans ; Female ; Male ; Aged, 80 and over ; Long-Term Care ; Prevalence ; Cross-Sectional Studies ; Anti-Bacterial Agents/therapeutic use ; Italy/epidemiology ; Inappropriate Prescribing

Background: Almost half of antimicrobial prescriptions in long-term care facilities (LTCFs) is inappropriate. This broad use might represent a strong contributor to antimicrobial resistance in these facilities. This study aimed to assess antibiotic use patterns and potential associated factors with a survey of LTCFs in the local health authority (LHA) of Novara.
Methods: A cross-sectional study was conducted in 25 LTCFs in the LHA of Novara following the healthcare-associated infection in LCTFs (HALT) protocol. Information on residents and facilities was assessed. Antibiotic usage and potential determinants were also estimated.
Results: In total, 1137 patients were screened for antibiotic usage. Mean age was 84.58 years (SD 9.77), and the majority were female (76.52%). Twenty-six were antibiotic users (prevalence rate 2.29%, 95%CI 1.50-3.33). Antimicrobials were mainly prescribed orally (84.62%). Potential risk factors for antibiotic prescription were catheter use (central and peripheral venous, p -values 0.0475 and 0.0034, respectively, and urinary, p -value 0.0008), immobilization ( p -value < 0.0001), and sex ( p -value 0.0486).
Conclusions: This study identified a low prevalence of antimicrobic consumption in LTCFs. Further surveillance studies are warranted to identify trends and changes in pathogen incidence and antimicrobial resistance and to inform public health authorities on the necessity of prudent use of antimicrobials in LCTFs.

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Keywords: antibiotic consumption; antibiotics; antimicrobial stewardship; long-term facilities

0 (Anti-Infective Agents)
0 (Anti-Bacterial Agents)

Date Created: 20221027 Date Completed: 20221028 Latest Revision: 20230118

20240829

PMC9603076

10.3390/ijerph192013412

36293992