A Case Study in Breast Density Evaluation Using Bioimpedance Measurements.

Publisher: MDPI Country of Publication: Switzerland NLM ID: 101204366 Publication Model: Electronic Cited Medium: Internet ISSN: 1424-8220 (Electronic) Linking ISSN: 14248220 NLM ISO Abbreviation: Sensors (Basel) Subsets: MEDLINE

Original Publication: Basel, Switzerland : MDPI, c2000-

Breast Density* ; Breast Neoplasms*/diagnostic imaging; Algorithms ; Breast/diagnostic imaging ; Female ; Humans ; Mammography/methods

(1) Background: As breast cancer studies suggest, a high percentage of breast density (PBD) may be related to breast cancer incidence. Although PBD screening is one of the strongest predictors of breast cancer risk, X-ray-based mammography evaluation is subjective. Therefore, new objective PBD measuring techniques are of interest. A case study analyzing the PBD of thirteen female participants using a bioimpedance-based method, the anomalies tracking circle (ATC), is described in this paper. (2) Methods: In the first stage, the breast bioimpedance of each participant was measured. Then, the participant breast density was determined by applying a mammogram just after the breast bioimpedance measurement stage. In the third stage, the ATC algorithm was applied to the measured bioimpedance data for each participant, and a results analysis was done. (3) Results: An ATC variation according to the breast density was observed from the obtained data, this allowed the use of classification techniques to determine the PBD. (4) Conclusions: The described breast density method is a promising approach that might be applied as an auxiliary tool to the mammography in order to obtain precise and objective results for evaluation of breast density and with that determine potential breast cancer risk.

J Natl Cancer Inst. 2007 Mar 7;99(5):386-95. (PMID: 17341730)
Breast Cancer Res. 2011;13(6):223. (PMID: 22114898)
Breast Cancer Res. 2009;11 Suppl 3:S4. (PMID: 20030879)
Ann Intern Med. 2009 Nov 17;151(10):716-26, W-236. (PMID: 19920272)
Lancet Oncol. 2009 Jun;10(6):569-80. (PMID: 19409844)
Ann Intern Med. 2016 Feb 16;164(4):268-78. (PMID: 26757021)
J Natl Cancer Inst. 2010 Aug 18;102(16):1224-37. (PMID: 20616353)
Cancer Epidemiol. 2011 Apr;35(2):188-93. (PMID: 20688593)
J Magn Reson. 2013 May;230:40-9. (PMID: 23435264)
Cancer Epidemiol Biomarkers Prev. 2006 Jun;15(6):1159-69. (PMID: 16775176)
J Cancer Res Ther. 2020 Oct-Dec;16(6):1258-1264. (PMID: 33342781)
N Engl J Med. 2002 Sep 19;347(12):886-94. (PMID: 12239257)
Cancer Causes Control. 2000 Aug;11(7):653-62. (PMID: 10977110)
Physiol Meas. 1998 Feb;19(1):61-75. (PMID: 9522388)
Eur Radiol. 2021 Jul;31(7):4839-4847. (PMID: 33409776)
Cancer Epidemiol Biomarkers Prev. 2006 Nov;15(11):2086-92. (PMID: 17119032)
Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):102-12. (PMID: 19124487)
Breast Cancer Res. 2013 Nov 04;15(6):R104. (PMID: 24188089)
Cancer Epidemiol Biomarkers Prev. 1998 Dec;7(12):1133-44. (PMID: 9865433)
BMC Cancer. 2011 Aug 02;11:330. (PMID: 21810248)
J Natl Cancer Inst. 2021 Oct 1;113(10):1299-1328. (PMID: 33544867)
J Natl Compr Canc Netw. 2010 Oct;8(10):1157-64; quiz 1165. (PMID: 20971840)
Womens Health Issues. 2017 Nov - Dec;27(6):692-699. (PMID: 28935360)
Asian Pac J Cancer Prev. 2016;17(1):65-71. (PMID: 26838256)

scholarship grant No. 436304 Consejo Nacional de Ciencia y Tecnología

Keywords: bioimpedance; breast cancer risk; breast density; in vivo evaluation

Date Created: 20220412 Date Completed: 20220413 Latest Revision: 20220423

20240628

PMC9002785

10.3390/s22072747

35408360