COVID-19 vaccine hesitancy among Ethiopian healthcare workers.

Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Original Publication: San Francisco, CA : Public Library of Science

COVID-19*/epidemiology ; COVID-19*/prevention & control; Health Personnel/*statistics & numerical data ; Vaccination Hesitancy/*statistics & numerical data; Adult ; Cross-Sectional Studies ; Ethiopia ; Female ; Humans ; Male ; Middle Aged ; Surveys and Questionnaires ; Vaccination/statistics & numerical data

Introduction: COVID-19 poses significant health and economic threat prompting international firms to rapidly develop vaccines and secure quick regulatory approval. Although COVID-19 vaccination priority is given for high-risk individuals including healthcare workers (HCWs), the success of the immunization efforts hinges on peoples' willingness to embrace these vaccines.
Objective: This study aimed to assess HCWs intention to be vaccinated against COVID-19 and the reasons underlying vaccine hesitancy.
Methods: A cross-sectional survey was conducted among HCWs in Addis Ababa, Ethiopia from March to July 2021. Data were collected from eligible participants from 18 health facilities using a pre-tested semi-structured questionnaire. Data were summarized using descriptive statistics and multivariable logistic regression was performed to explore factors associated with COVID-19 vaccine hesitancy. A p<0.05 was considered statistically significant.
Results: A total of 614 HCWs participated in the study, with a mean age of 30.57±6.87 years. Nearly two-thirds (60.3%) of HCWs were hesitant to use the COVID-19 vaccine. Participants under the age of 30 years were approximately five times more likely to be hesitant to be vaccinated compared to those over the age of 40 years. HCWs other than medical doctors and/or nurses (AOR = 2.1; 95%CI; 1.1, 3.8) were more likely to be hesitant for COVID-19 vaccine. Lack of believe in COVID-19 vaccine benefits (AOR = 2.5; 95%CI; 1.3, 4.6), lack of trust in the government (AOR = 1.9; 95%CI; 1.3, 3.1), lack of trust science to produce safe and effective vaccines (AOR = 2.6; 95%CI; 1.6, 4.2); and concern about vaccine safety (AOR = 3.2; 95%CI; 1.9, 5.4) were also found to be predictors of COVID-19 vaccine hesitancy.
Conclusion: COVID-19 vaccine hesitancy showed to be high among HCWs. All concerned bodies including the ministry, regional health authorities, health institutions, and HCWs themselves should work together to increase COVID-19 vaccine uptake and overcome the pandemic.
Competing Interests: The authors have declared that no competing interests exist.

JAMA Health Forum. 2021 Mar 1;2(3):e210434. (PMID: 36218456)
Vaccines (Basel). 2021 Feb 03;9(2):. (PMID: 33546165)
JMIR Public Health Surveill. 2021 Nov 17;7(11):e30642. (PMID: 34653016)
NPJ Vaccines. 2021 Apr 14;6(1):54. (PMID: 33854072)
Early Hum Dev. 2020 Oct 1;:105213. (PMID: 33032879)
Vaccines (Basel). 2021 Jun 27;9(7):. (PMID: 34199143)
Gastroenterol Hepatol Bed Bench. 2013 Winter;6(1):14-7. (PMID: 24834239)
Vaccines (Basel). 2021 Feb 16;9(2):. (PMID: 33669441)
Vaccine. 2018 Aug 23;36(35):5273-5281. (PMID: 30061026)
N Engl J Med. 2020 Oct 29;383(18):1701-1703. (PMID: 32846056)
J Autoimmun. 2020 May;109:102433. (PMID: 32113704)
Vaccine. 2021 Sep 24;39(40):5762-5768. (PMID: 34481700)
Front Public Health. 2020 May 28;8:216. (PMID: 32574299)
Psychol Med. 2021 Jul;51(10):1763-1769. (PMID: 32513320)
Clinicoecon Outcomes Res. 2021 Apr 22;13:279-287. (PMID: 33935506)
Vaccine. 2021 May 18;39(21):2833-2842. (PMID: 33896661)
Vaccine. 2015 Aug 14;33(34):4161-4. (PMID: 25896383)
PLoS One. 2021 Sep 3;16(9):e0257109. (PMID: 34478470)
Hum Vaccin Immunother. 2020 Nov 1;16(11):2586-2593. (PMID: 32693678)
Pragmat Obs Res. 2020 Oct 29;11:103-109. (PMID: 33154695)
N Engl J Med. 2009 May 7;360(19):1981-8. (PMID: 19420367)
J Multidiscip Healthc. 2021 May 28;14:1233-1243. (PMID: 34093019)
Br J Health Psychol. 2022 May;27(2):300-319. (PMID: 34250684)
J Med Virol. 2021 Jul;93(7):4280-4291. (PMID: 33644891)

Date Created: 20211217 Date Completed: 20220110 Latest Revision: 20230921

20231215

PMC8682893

10.1371/journal.pone.0261125

34919597