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Cannabis Use is an Independent Risk Factor for Manic Episode: A Report from 380,265 Bipolar Inpatients.

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  • معلومة اضافية
    • المصدر:
      Publisher: Informa Healthcare Country of Publication: England NLM ID: 9602153 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2491 (Electronic) Linking ISSN: 10826084 NLM ISO Abbreviation: Subst Use Misuse Subsets: MEDLINE
    • بيانات النشر:
      Publication: London : Informa Healthcare
      Original Publication: Monticello, NY : Dekker, 1996-
    • الموضوع:
      Bipolar Disorder*/epidemiology ; Bipolar Disorder*/psychology ; Cannabis* ; Substance-Related Disorders*/epidemiology; Adolescent ; Adult ; Cross-Sectional Studies ; Humans ; Inpatients ; Mania ; Research Report ; Risk Factors
    • نبذة مختصرة :
      Objectives: To evaluate the odds for bipolar disorder (BP) mania and depression-related hospitalization due to cannabis use disorders (CUD).
      Methods: We conducted a cross-sectional study using the national inpatient sample (NIS), and included adult BP hospitalizations sub-grouped by manic (N = 209,785) versus depressive episodes (N = 170480). A logistic regression model was used to evaluate adjusted odds ratio (aOR) of association between CUD and BP-mania-related hospitalizations and was adjusted for demographics confounders, psychiatric comorbidities and other substance use disorders (SUD).
      Results: Comorbidities were less prevalent in BP mania compared to BP depression: anxiety disorders (22.7% vs. 35.3%), PTSD (8.7% vs. 14.3%), and personality disorders (15.4% vs. 20.5%). Among SUD, methamphetamine (aOR 1.27, 95%CI 1.22 - 1.32) and CUD (aOR 1.53, 95%CI 1.50 - 1.56) had increased odds for hospitalization for BP mania.
      Conclusion: CUD increases the odds for hospitalization for BP manic episode by 53%. Due to the rising prevalence of cannabis use among patients with BP it is important to provide substance use counseling/psychoeducation and discourage cannabis use among youth to prevent long-term adverse consequences.
    • Contributed Indexing:
      Keywords: Manic episode*; manic symptoms*; national inpatient sample*
    • الموضوع:
      Date Created: 20211213 Date Completed: 20220421 Latest Revision: 20220501
    • الموضوع:
      20240829
    • الرقم المعرف:
      10.1080/10826084.2021.2012690
    • الرقم المعرف:
      34895014