Orbital cellulitis and cavernous sinus thrombosis with contralateral sinus disease in a COVID-19 positive adolescent patient.

Publisher: Informa Healthcare Country of Publication: England NLM ID: 8301221 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5108 (Electronic) Linking ISSN: 01676830 NLM ISO Abbreviation: Orbit Subsets: MEDLINE

Publication: London : Informa Healthcare
Original Publication: Amsterdam : Aeolus Press, [1982-

Orbital Cellulitis*/diagnostic imaging ; Orbital Cellulitis*/drug therapy ; Cavernous Sinus Thrombosis*/diagnostic imaging ; Cavernous Sinus Thrombosis*/etiology ; COVID-19* ; Cavernous Sinus*/diagnostic imaging ; Thrombosis*/complications; Humans ; Male ; Adolescent ; Cellulitis/complications

Patients with COVID-19 have been reported to have elevated coagulation factors, which is a well-documented cause of venous thromboembolism events such as deep vein thrombosis and pulmonary embolism. Other venous thrombotic events, however, such as cavernous sinus thrombosis (CST) have been less commonly observed, specifically in combination with primary orbital cellulitis. Due to its unique anatomic location, the cavernous sinus is susceptible to thrombophlebitis processes including septic thrombosis and thrombosis most commonly from sinusitis. Many studies have shown that in the antibiotic era thromboembolic events of the cavernous sinus are less common due to infection spread from the orbit or facial region. This case report describes a 17-year-old COVID-19 positive male who presented with a left-sided primary orbital cellulitis with CST without radiographic evidence of ipsilateral sinus disease.

Keywords: COVID-19; Cavernous sinus thrombosis; cerebral venous thrombosis; hypercoagulable; primary orbital cellulitis; sinus disease

Date Created: 20211201 Date Completed: 20230517 Latest Revision: 20230517

20230517

10.1080/01676830.2021.2006722

34847834