Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Tympanic Membrane Retractions in patients with Williams Syndrome: A Controlled Study.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: Thieme Country of Publication: Brazil NLM ID: 101637652 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1809-9777 (Print) Linking ISSN: 18094864 NLM ISO Abbreviation: Int Arch Otorhinolaryngol Subsets: PubMed not MEDLINE
    • بيانات النشر:
      Publication: Oct. 2013- : Rio de Janeiro, Brazil : Thieme
      Original Publication: [São Paulo, SP : Fundação Otorrinolaringologia]
    • نبذة مختصرة :
      Introduction  The role of elastin in tympanic retractions and chronic otitis media is not well established. Williams Syndrome (WS), a pathology related to a mutation in the elastin gene, could generate tympanic retractions. Objective  To compare the prevalence of tympanic retractions among patients with WS and controls. Methods  WS patients ( n  = 43 ears) and controls ( n  = 130 ears) were evaluated by digital otoscopic examination and the degree of tympanic membrane retraction was classified by 2 blinded experienced otolaryngologists. Results  The agreement rate between the evaluators was 71.1% for pars tensa and 65% for pars flaccida retraction ( p  < 0.001). The pars tensa and pars flaccida retractions are present in patients with WS after an adjusted residue of respectively - 2.8 and - 2.6 ( p  = 0.011 and p  = 0.022) compared with controls. Conclusions  Tympanic membrane retractions are not more common in the WS group when compared with controls.
      (Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).)
    • References:
      Acta Anat (Basel). 1988;131(4):332-7. (PMID: 3376739)
      Am J Otolaryngol. 1990 Jan-Feb;11(1):10-7. (PMID: 2321706)
      Acta Otorhinolaryngol Belg. 1991;45(3):265-77. (PMID: 1950545)
      Arch Otolaryngol Head Neck Surg. 1991 Jun;117(6):627-34. (PMID: 2036184)
      J Laryngol Otol. 1981 Oct;95(10):1011-22. (PMID: 7197705)
      Arch Otolaryngol Head Neck Surg. 1987 Apr;113(4):380-5. (PMID: 3814387)
      Arch Otolaryngol Head Neck Surg. 1992 Dec;118(12):1298-305. (PMID: 1449688)
      Acta Otolaryngol. 1981 Nov-Dec;92(5-6):501-12. (PMID: 7315268)
      Biometrics. 1977 Mar;33(1):159-74. (PMID: 843571)
      Ann Otol Rhinol Laryngol. 1989 Oct;98(10):761-6. (PMID: 2478069)
    • Contributed Indexing:
      Keywords: chronic otitis media; elastin; williams syndrome
    • الموضوع:
      Date Created: 20210811 Latest Revision: 20210812
    • الموضوع:
      20240829
    • الرقم المعرف:
      PMC8321626
    • الرقم المعرف:
      10.1055/s-0040-1715151
    • الرقم المعرف:
      34377182