Comparison of Diagnostic Performance between Perfusion-Related Intravoxel Incoherent Motion DWI and Dynamic Contrast-Enhanced MRI in Rectal Cancer.

Publisher: Hindawi Country of Publication: United States NLM ID: 101277751 Publication Model: eCollection Cited Medium: Internet ISSN: 1748-6718 (Electronic) Linking ISSN: 1748670X NLM ISO Abbreviation: Comput Math Methods Med Subsets: MEDLINE

Publication: 2011-2024 : New York : Hindawi
Original Publication: London : Taylor & Francis, c2006-

Diffusion Magnetic Resonance Imaging/*methods ; Magnetic Resonance Imaging/*methods ; Rectal Neoplasms/*diagnostic imaging; Adenocarcinoma/blood supply ; Adenocarcinoma/diagnostic imaging ; Adenocarcinoma/pathology ; Adult ; Aged ; Aged, 80 and over ; Cell Differentiation ; Computational Biology ; Contrast Media ; Diffusion Magnetic Resonance Imaging/statistics & numerical data ; Female ; Humans ; Image Interpretation, Computer-Assisted/methods ; Image Interpretation, Computer-Assisted/statistics & numerical data ; Magnetic Resonance Imaging/statistics & numerical data ; Male ; Middle Aged ; Neoplasm Grading ; Rectal Neoplasms/blood supply ; Rectal Neoplasms/pathology ; Retrospective Studies

This study was aimed to determine the diagnostic performance of perfusion-related parameters derived from intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) by comparing them with quantitative parameters from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) based on differentiation grades of rectal cancer. We retrospectively analyzed 98 patients with rectal cancer. Perfusion-related IVIM parameters ( D ^∗ , f , and f · D ^∗ ) and quantitative DCE parameters ( K ^trans , K ep , V e , and V p ) were obtained by plotting the volume-of-interest on in-house software. Furthermore, we compared the difference and diagnostic performance of all well-moderately and poorly differentiated rectal cancer parameters. Finally, we analyzed the correlation between those DCE and IVIM parameters and pathological differentiation grade. The values of f , K ^trans , and K ep significantly differentiated poor and well-moderate rectal cancers. K ^trans achieved the highest area under the curve (AUC) value compared to perfusion-related IVIM and DCE parameters. Furthermore, K ^trans showed a better correlation with pathological differentiation grade than f . The diagnostic efficiency of DCE-MRI was greater than perfusion-related IVIM parameters. The f value derived from perfusion-related IVIM offered a diagnostic performance similar to DCE-MRI for patients with renal insufficiency.
Competing Interests: The author declares no conflicts of interest.
(Copyright © 2021 Ming Li et al.)

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0 (Contrast Media)

Date Created: 20210809 Date Completed: 20211124 Latest Revision: 20211124

20240628

PMC8346302

10.1155/2021/5095940

34367318