Comparing the influence of stimulus size and contrast on the perception of moving gratings and random dot patterns-A registered report protocol.

Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Original Publication: San Francisco, CA : Public Library of Science

Motion Perception/*physiology ; Neurons/*physiology ; Photic Stimulation/*methods ; Visual Cortex/*physiology ; Visual Fields/*physiology ; Visual Pathways/*physiology ; Visual Perception/*physiology; Humans

Modern accounts of visual motion processing in the primate brain emphasize a hierarchy of different regions within the dorsal visual pathway, especially primary visual cortex (V1) and the middle temporal area (MT). However, recent studies have called the idea of a processing pipeline with fixed contributions to motion perception from each area into doubt. Instead, the role that each area plays appears to depend on properties of the stimulus as well as perceptual history. We propose to test this hypothesis in human subjects by comparing motion perception of two commonly used stimulus types: drifting sinusoidal gratings (DSGs) and random dot patterns (RDPs). To avoid potential biases in our approach we are pre-registering our study. We will compare the effects of size and contrast levels on the perception of the direction of motion for DSGs and RDPs. In addition, based on intriguing results in a pilot study, we will also explore the effects of a post-stimulus mask. Our approach will offer valuable insights into how motion is processed by the visual system and guide further behavioral and neurophysiological research.
Competing Interests: The authors have declared that no competing interests exist.

Nature. 2001 Dec 20-27;414(6866):905-8. (PMID: 11780062)
R Soc Open Sci. 2019 Mar 27;6(3):190114. (PMID: 31032060)
J Neurosci. 1996 Dec 1;16(23):7733-41. (PMID: 8922429)
Sci Rep. 2018 May 29;8(1):8357. (PMID: 29844426)
Trends Cogn Sci. 2004 Oct;8(10):457-64. (PMID: 15450510)
J Neurosci. 1988 Jun;8(6):2201-11. (PMID: 3385495)
Neuron. 2017 Jul 19;95(2):436-446.e3. (PMID: 28689980)
Elife. 2016 Nov 23;5:. (PMID: 27879201)
PLoS Comput Biol. 2016 Dec 15;12(12):e1005225. (PMID: 27977679)
Vision Res. 1993 Mar-Apr;33(5-6):791-8. (PMID: 8351850)
Elife. 2016 May 26;5:. (PMID: 27228283)
Nature. 2003 Jul 17;424(6946):312-5. (PMID: 12867982)
J Neurophysiol. 1986 Jun;55(6):1328-39. (PMID: 3734858)
Nature. 1999 Jun 10;399(6736):575-9. (PMID: 10376597)
Nat Neurosci. 2005 Dec;8(12):1647-50. (PMID: 16306892)
J Neurophysiol. 1997 Apr;77(4):1906-23. (PMID: 9114244)
J Vis. 2008 Jul 07;8(9):2.1-13. (PMID: 18831638)
Annu Rev Neurosci. 2005;28:157-89. (PMID: 16022593)
Annu Rev Vis Sci. 2020 Sep 15;6:335-362. (PMID: 32936737)
J Vis. 2009 Jan 21;9(1):25.1-15. (PMID: 19271895)
Nature. 1996 Aug 8;382(6591):539-41. (PMID: 8700227)
Neuron. 2005 Feb 3;45(3):361-6. (PMID: 15694323)
J Vis. 2011 Feb 03;11(2):. (PMID: 21292831)
Trends Cogn Sci. 2005 Feb;9(2):46-52. (PMID: 15668096)
Exp Brain Res. 1992;88(2):389-400. (PMID: 1577111)
J Opt Soc Am A Opt Image Sci Vis. 1997 Jan;14(1):1-12. (PMID: 8988615)
J Neurosci. 1986 Jan;6(1):145-57. (PMID: 3944616)
Cereb Cortex. 1999 Jan-Feb;9(1):90-100. (PMID: 10022498)
J Vis. 2015;15(13):21. (PMID: 26401628)
Nature. 2001 Feb 22;409(6823):1040-2. (PMID: 11234012)
Nature. 1982 Dec 9;300(5892):523-5. (PMID: 7144903)
Annu Rev Neurosci. 2017 Jul 25;40:211-230. (PMID: 28418757)
J Neurosci. 1986 Jan;6(1):134-44. (PMID: 3944614)
Nat Neurosci. 2006 Nov;9(11):1421-31. (PMID: 17041595)
J Neurosci. 1992 Jun;12(6):2331-55. (PMID: 1607944)
Neuron. 2002 Dec 5;36(5):791-804. (PMID: 12467584)
Vision Res. 1998 Mar;38(5):743-61. (PMID: 9604103)
Physiol Rep. 2017 Mar;5(5):. (PMID: 28275107)
Nature. 1995 Aug 10;376(6540):507-9. (PMID: 7637781)
Vision Res. 2006 Aug;46(16):2465-74. (PMID: 16542700)
Vision Res. 2005 Jul;45(16):2059-64. (PMID: 15845238)
Neuroimage. 2006 Feb 15;29(4):1326-35. (PMID: 16185899)
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13914-9. (PMID: 12368476)
J Neurosci. 1992 Dec;12(12):4745-65. (PMID: 1464765)
J Neurophysiol. 2021 May 1;125(5):1851-1882. (PMID: 33656951)
Nature. 1990 Jul 12;346(6280):174-7. (PMID: 2366872)
Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):E972-80. (PMID: 22308392)
J Neurosci. 2011 Jan 26;31(4):1279-83. (PMID: 21273412)

Date Created: 20210621 Date Completed: 20211118 Latest Revision: 20211118

20250114

PMC8216547

10.1371/journal.pone.0253067

34153081