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Randomized study of remote telehealth genetic services versus usual care in oncology practices without genetic counselors.

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  • معلومة اضافية
    • المصدر:
      Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: [Malden, MA] : John Wiley & Sons Ltd., c2012-
    • الموضوع:
      Genetic Services/*statistics & numerical data ; Medical Oncology/*statistics & numerical data ; Telemedicine/*statistics & numerical data; Anxiety/epidemiology ; Counselors ; Depression/epidemiology ; Female ; Genetic Carrier Screening/statistics & numerical data ; Genetic Counseling/statistics & numerical data ; Genetic Testing/statistics & numerical data ; Humans ; Male ; Middle Aged ; Mutation Rate ; Socioeconomic Factors ; Telemedicine/methods ; Telephone/statistics & numerical data ; Time Factors ; Videoconferencing/statistics & numerical data
    • نبذة مختصرة :
      Purpose: To examine the benefit of telehealth over current delivery options in oncology practices without genetic counselors.
      Methods: Participants meeting cancer genetic testing guidelines were recruited to this multi-center, randomized trial comparing uptake of genetic services with remote services (telephone or videoconference) to usual care in six predominantly community practices without genetic counselors. The primary outcome was the composite uptake of genetic counseling or testing. Secondary outcomes compare telephone versus videoconference services.
      Results: 147 participants enrolled and 119 were randomized. Eighty percent of participants in the telehealth arm had genetic services as compared to 16% in the usual care arm (OR 30.52, p < 0.001). Five genetic mutation carriers (6.7%) were identified in the telehealth arm, compared to none in the usual care arm. In secondary analyses, factors associated with uptake were lower anxiety (6.77 vs. 8.07, p = 0.04) and lower depression (3.38 vs. 5.06, p = 0.04) among those who had genetic services. There were no significant differences in change in cognitive or affective outcomes immediately post-counseling and at 6 and 12 months between telephone and videoconference arms.
      Conclusion: Telehealth increases uptake of genetic counseling and testing at oncology practices without genetic counselors and could significantly improve identification of genetic carriers and cancer prevention outcomes.
      (© 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.)
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    • Grant Information:
      Basser Center
    • Contributed Indexing:
      Keywords: alternative service delivery; cancer genetics; cancer predisposition syndromes; genetic counseling; genetic testing; genetics; telegenetics; telehealth; telemedicine
    • الموضوع:
      Date Created: 20210608 Date Completed: 20211231 Latest Revision: 20211231
    • الموضوع:
      20250114
    • الرقم المعرف:
      PMC8267134
    • الرقم المعرف:
      10.1002/cam4.3968
    • الرقم المعرف:
      34102012