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Trace Element and Mineral Levels in Serum, Hair, and Urine of Obese Women in Relation to Body Composition, Blood Pressure, Lipid Profile, and Insulin Resistance.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Basel, Switzerland : MDPI, 2011-
    • الموضوع:
      Hair/*chemistry ; Minerals/*analysis ; Obesity/*metabolism ; Serum/*chemistry ; Trace Elements/*analysis ; Triglycerides/*blood; Adult ; Aged ; Body Composition ; Case-Control Studies ; Female ; Humans ; Insulin Resistance ; Logistic Models ; Middle Aged ; Minerals/blood ; Minerals/urine ; Obesity/blood ; Obesity/urine ; Trace Elements/blood ; Trace Elements/urine
    • نبذة مختصرة :
      The objective of this study was to evaluate serum, hair, and urinary trace element and mineral content in normal-weight and obese women in relation to metabolic risk factors. A total of 80 women aged 30-70 y.o. were enrolled in the obese group (n = 40) and normal-weight group (n = 40). Serum, hair, and urinary trace element and mineral levels were assessed using inductively coupled plasma spectrometry. Body fat percentage was evaluated using bioimpedance. Obese subjects were characterized by significantly higher body fat percentage, blood pressure, serum triglyceride concentration, and insulin resistance. Serum Ca, Fe, Mg, Se, V, Zn levels, hair Fe, Mg, V content, and urinary Se and V concentrations were found to be lower in obese subjects as compared to lean controls. In turn, serum Cu and urinary Fe levels in obese women were characterized by a significant increase. In multiple regression models serum Cu, Se, and Zn levels were significantly associated with BMI even after adjustment for blood biochemistry, body composition, and blood pressure. Serum trace element and mineral levels also significantly contributed to group discrimination. These findings allow to propose that obesity-associated disturbances in trace element and mineral status may at least partially contribute to metabolic risk in obese subjects.
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    • Grant Information:
      0856-2020-0008 Russian Ministry of Science and Higher Education
    • Contributed Indexing:
      Keywords: copper; insulin resistance; metabolic syndrome; obesity; selenium
    • الرقم المعرف:
      0 (Minerals)
      0 (Trace Elements)
      0 (Triglycerides)
    • الموضوع:
      Date Created: 20210602 Date Completed: 20210922 Latest Revision: 20210922
    • الموضوع:
      20221213
    • الرقم المعرف:
      PMC8147795
    • الرقم المعرف:
      10.3390/biom11050689
    • الرقم المعرف:
      34064348