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Three pediatric patients with primary hyperparathyroidism caused by parathyroid adenoma.

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  • المؤلفون: Oh A;Oh A; Lee Y; Lee Y; Yoo HW; Yoo HW; Choi JH; Choi JH
  • المصدر:
    Annals of pediatric endocrinology & metabolism [Ann Pediatr Endocrinol Metab] 2022 Jun; Vol. 27 (2), pp. 142-147. Date of Electronic Publication: 2021 May 20.
  • نوع النشر :
    Case Reports
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Korean Society of Pediatric Endocrinology Country of Publication: Korea (South) NLM ID: 101588279 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2287-1012 (Print) Linking ISSN: 22871012 NLM ISO Abbreviation: Ann Pediatr Endocrinol Metab Subsets: PubMed not MEDLINE
    • بيانات النشر:
      Original Publication: Seoul : Korean Society of Pediatric Endocrinology
    • نبذة مختصرة :
      Primary hyperparathyroidism (PHPT) is a hypercalcemia disorder with inappropriately normal or increased serum parathyroid hormone (PTH) levels resulting from excessive secretion of PTH from one or more of the parathyroid glands. PHPT is uncommon in infants and children, with an estimated incidence of 2-5 cases per 100,000 persons. Patients with PHPT usually present with bone pain, urolithiasis, or nephrolithiasis, as well as nonspecific symptoms such as fatigue and weakness. Asymptomatic hypercalcemia may also be detected incidentally. Only a few cases of pediatric PHPT have been reported in Korea. We present three patients (a 9-year-old girl, a 14-year-old boy, and a 14-year-old girl) with PHPT who manifested variable clinical features of hypercalcemia. The first and second patients each had a parathyroid adenoma and presented with abdominal pain caused by pancreatitis and a ureter stone, respectively. The third patient had an ectopic mediastinal parathyroid adenoma and presented with gait disturbance and weakness of the lower extremities. All of the patients underwent surgical resection of parathyroid adenoma, and their serum calcium levels subsequently normalized without medication.
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    • Grant Information:
      NRF2021R1F1A104593011 National Research Foundation of Korea; Ministry of Science and ICT
    • Contributed Indexing:
      Keywords: Hypercalcemia; Hyperparathyroidism; Parathyroid adenoma
    • الموضوع:
      Date Created: 20210521 Latest Revision: 20240831
    • الموضوع:
      20240831
    • الرقم المعرف:
      PMC9260372
    • الرقم المعرف:
      10.6065/apem.2142006.003
    • الرقم المعرف:
      34015897