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A comparison of the outcomes of dexmedetomidine and remifentanil with sufentanil-based general anesthesia in pediatric patients for the transthoracic device closure of ventricular septal defects.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: BioMed Central Country of Publication: England NLM ID: 101265113 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-8090 (Electronic) Linking ISSN: 17498090 NLM ISO Abbreviation: J Cardiothorac Surg Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: [London] : BioMed Central, 2006-
    • الموضوع:
      Dexmedetomidine/*therapeutic use ; Heart Septal Defects, Ventricular/*surgery ; Pain, Postoperative/*drug therapy ; Remifentanil/*therapeutic use ; Respiration, Artificial/*methods ; Sufentanil/*therapeutic use; Analgesia, Patient-Controlled/methods ; Anesthesia, General ; Child ; Child, Preschool ; Female ; Hemodynamics ; Humans ; Infant ; Length of Stay ; Male ; Middle Aged ; Patient Safety ; Retrospective Studies
    • نبذة مختصرة :
      Objective: To compare the safety and efficacy of dexmedetomidine and remifentanil with sufentanil-based general anesthesia for the transthoracic device closure of ventricular septal defects (VSDs) in pediatric patients.
      Methods: A retrospective analysis was performed on 60 children undergoing the transthoracic device closure of VSDs from January 2019 to June 2020. The patients were divided into two groups based on different anesthesia strategies, including 30 cases in group R (dexmedetomidine- and remifentanil-based general anesthesia) and 30 cases in group S (sufentanil-based general anesthesia).
      Results: There was no significant difference in preoperative clinical information, hemodynamics before induction and after extubation, postoperative pain scores, or length of hospital stay between the two groups. However, the hemodynamic data of group R were significantly lower than those of group S at the time points of anesthesia induction, skin incision, thoracotomy, incision closure, and extubation. The amount of intravenous patient-controlled analgesia (PCA), the duration of mechanical ventilation, and the length of the intensive care unit (ICU) stay in group R were significantly less than those in group S.
      Conclusion: Dexmedetomidine combined with remifentanil-based general anesthesia for the transthoracic device closure of VSDs in pediatric patients is safe and effective.
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    • Contributed Indexing:
      Keywords: CHD; Cardiac anesthesia; Cardiac intervention; Septal defects
    • الرقم المعرف:
      67VB76HONO (Dexmedetomidine)
      AFE2YW0IIZ (Sufentanil)
      P10582JYYK (Remifentanil)
    • الموضوع:
      Date Created: 20210424 Date Completed: 20210701 Latest Revision: 20210701
    • الموضوع:
      20231215
    • الرقم المعرف:
      PMC8063160
    • الرقم المعرف:
      10.1186/s13019-021-01498-8
    • الرقم المعرف:
      33892771