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COVID-19 Infection-Related Weight Loss Decreases Eating/Swallowing Function in Schizophrenic Patients.

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  • معلومة اضافية
    • المصدر:
      Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Basel, Switzerland : MDPI Publishing
    • الموضوع:
      Weight Loss*; COVID-19/*complications ; Deglutition Disorders/*etiology ; Feeding and Eating Disorders/*etiology ; Schizophrenia/*complications; Aged ; COVID-19/physiopathology ; COVID-19/psychology ; Deglutition Disorders/physiopathology ; Deglutition Disorders/psychology ; Eating/physiology ; Eating/psychology ; Feeding and Eating Disorders/physiopathology ; Feeding and Eating Disorders/psychology ; Female ; Humans ; Male ; Middle Aged ; Nutritional Status ; Schizophrenia/virology
    • نبذة مختصرة :
      Background: In older people with psychoneurological diseases, COVID-19 infection may be associated with a risk of developing or exacerbating dysphagia. The aim of the present study was to examine the relationship between eating/swallowing function and COVID-19 infection.
      Methods: Subjects were 44 inpatients with confirmed COVID-19 infection being treated for schizophrenia in a psychiatric ward. Eating function was assessed using the Food Intake Level Scale (FILS) before and after infection. We also evaluated age, comorbidities, COVID-19 hospital stay, obesity index, weight loss rate, and chlorpromazine equivalent.
      Results: Subjects had a mean age of 68.86 years. Pre-infection, 20 subjects had a FILS score of 7-9 (presence of eating/swallowing disorder) and 24 subjects had a score of 10 (normal). Eating function after infection resolution showed decreasing FILS score compared to that before infection in 14 subjects (74.14 years). Six subjects (79.3 years) transitioned from oral feeding to parenteral feeding. A ≥ 10% weight loss during infection treatment was significantly associated with decreased eating function and a transition to parenteral feeding. Chlorpromazine equivalents, comorbidities, and number of days of hospitalization showed no associations with decreased eating function.
      Conclusions: Preventing malnutrition during treatment for COVID-19 infection is important for improving post-infection life prognosis and maintaining quality of life (QOL).
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    • Contributed Indexing:
      Keywords: COVID-19; cachexia; dysphagia; schizophrenia; weight loss
    • الموضوع:
      Date Created: 20210403 Date Completed: 20210412 Latest Revision: 20210428
    • الموضوع:
      20221213
    • الرقم المعرف:
      PMC8065805
    • الرقم المعرف:
      10.3390/nu13041113
    • الرقم المعرف:
      33805263